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Cardiovascular diseases (CVDs) constitute one of the leading global health burdens, accounting for nearly 50% of all deaths worldwide. Rapid urbanization, lifestyle transitions, psychosocial stress, socioeconomic factors, and changing dietary pattern...

Background: In this study, a cultivated mushroom (Buchwaldoboletus sp.) polysaccharide (BSP60) was prepared. Methods: The protective effect of BSP60 on ulcerative colitis (UC) was evaluated using a dextran sulphate sodium (DSS)-induced murine model o...

Background: Ginsenoside Rh2 (Rh2), a bioactive metabolite of Panax ginseng, has documented anticancer effects, but its role in cancer–immune crosstalk remains incompletely defined. Thus, we aimed to investigate the role of Rh2 in hepatocellular...

Background/Objectives: The aim of this study was to produce fermented sheep milk and to evaluate its microbiological properties. In addition, the survival of six probiotic strains was assessed using a standardized static in vitro digestion model. Met...

Background: Geographic peripherality in Israel is linked to poorer health outcomes and may disproportionately affect patients requiring chronic therapies such as hemodialysis (HD). Though malnutrition and inflammation are strong predictors of morbidi...

Background: Alcohol use is a major global health burden and is causally linked to several wholly alcohol-attributed conditions, including alcohol use disorder (AUD) and alcohol-associated liver disease (ALD). Current therapeutic options remain limite...

Maternal nutritional status before and during pregnancy is an important modifiable factor that may influence foetal development and long-term offspring health. Both undernutrition and excessive maternal body weight have been associated with adverse m...

Background/Objectives: Diet quality is relevant to athlete health and recovery, yet practical methods for assessing dietary patterns in elite sporting environments remain limited. This exploratory study aimed to examine the relationship between skin...

Background/Objectives: Previous publications have primarily examined the individual roles of nutrients during fetal development. However, growing evidence suggests that one-carbon (1C) metabolism nutrients, including choline and key B vitamins, act s...

Background/Objectives: Although cow’s milk allergy is the most common food allergy in infants, its diagnosis remains challenging. Conventional allergy tests, including skin-prick testing and serum-specific IgE, can support the diagnosis in case...

Background/Objectives: Total or partial pancreatectomy is associated with significant metabolic stress and high risk of postoperative malnutrition. Accurate estimation of resting energy expenditure (REE) is essential, as predictive equations may not...

Background: Scurvy, a condition caused by vitamin C deficiency, has traditionally been considered eradicated in high-income countries (HICs; World Bank classification). However, emerging evidence suggests its re-emergence within identifiable vulnerab...

Introduction: Hepatic fibrosis represents a critical intermediate stage in the progression from chronic liver disease to cirrhosis and ultimately hepatocellular carcinoma. Spirulina platensis, a microorganism rich in bioactive compounds, contains sev...

Background/Objectives: Early childhood is a critical period for establishing lifelong dietary patterns, and early learning environments play a central role in shaping children’s eating behaviors. However, many childhood educators receive limite...

Background/Objectives: Resveratrol, a natural polyphenol with anti-inflammatory and antioxidant properties, has emerged as a promising adjunctive agent in periodontal therapy. This systematic review and meta-analysis evaluated evidence from in vitro,...

Background/Objectives: Postoperative pulmonary complications (PPCs) are a major source of morbidity following cardiac surgery, particularly in older adults. While malnutrition is linked to adverse outcomes, the optimal screening tool for identifying...

Background/Objectives: Diet quality among university students is influenced by multiple behavioural and lifestyle factors, yet limited research has examined how cannabis use relates to overall diet quality within this population. This study examined...

The circadian rhythm is an internal timing system formed by the body’s adaptation to the Earth’s rotation, which helps maintain homeostasis by regulating physiological, metabolic, and behavioral activities. The gut microbiota (GM), the la...

Dementia is a growing challenge for aging societies, and effective prevention depends on identifying risk factors that can be addressed early, before cognitive decline becomes clinically apparent. Declining oral and dental function, particularly toot...

Evidence from clinical trials indicates that dietary protein plays an important and often underappreciated role in lipoprotein lipid metabolism. For this narrative review, literature searches were conducted in the PubMed and Cochrane Central Register...

Alzheimer’s disease (AD) is a multifactorial neurodegenerative disorder characterized by impaired glucose metabolism, mitochondrial dysfunction, inflammation, oxidative stress, and progressive cognitive decline. Because currently available phar...

Micronutrients, including essential minerals and vitamins, together with bioactive molecules such as polyphenols, flavonoids, and milk-derived proteins, are fundamental to human health [...]

Background: Tuber indicum is a rare edible and medicinal ectomycorrhizal fungus, and the polysaccharide fractions have attracted extensive research attention owing to their potent immunomodulatory potential. Objective/Methods: To systematically chara...

Background/Objectives: This study aimed to identify dietary patterns among community-dwelling older adults in northern Thailand and examine their associations with nutrient intake, serum biomarkers, and anthropometric indicators. Methods: A cross-sec...

Background/Objectives: Accurate estimation of meal composition from food images can support safer and more reliable insulin bolus decision-making for individuals with Type 1 diabetes. Existing food recognition and nutrition estimation systems are oft...

Background: Diet plays a central role in the development of chronic diseases, making nutrition-focused interventions a powerful tool for improving population health. However, substantial gaps in nutrition education persist in the U.S. medical educati...

Background/Objectives: The gut–brain axis and systemic metabolic dysregulation are increasingly implicated in Alzheimer’s disease (AD) pathogenesis. This study aimed to characterize gut microbiota and plasma metabolomic profiles associate...

Objectives: Human milk composition changes across lactation, but paired within-subject proteomic analyses comparing longitudinal trajectories in term and preterm milk remain limited. We aimed to characterize stage-associated proteomic changes within...

Background: Malnutrition is increasingly recognized as an important determinant of prognosis in patients with heart failure (HF). The Geriatric Nutritional Risk Index (GNRI) is a simple nutritional assessment tool associated with adverse cardiovascul...

Background/Objectives: The World Health Organization recommends continued breastfeeding for up to 2 years of age. However, because breast milk contains less iron than formula milk, prolonged exclusive breastfeeding may increase the risk of iron defic...

Background/Objectives: Diet-disease-related knowledge (DDRK) is theorized to foster healthier lifestyles; however, the structural interconnectedness between nutritional knowledge and personal biomarker awareness is not well understood. This study aim...

Background: The Nutrition Improvement Program has been implemented in China for over a decade; however, its assessment in Hubei Province has not yet been systematically reported. This study evaluated the implementation outcomes of the Rural Compulsor...

Background/Objectives: Hormonal changes during the perimenopausal period are linked to alterations in lipid metabolism and increased cardiovascular disease risk. Dairy polar lipids (PLs), including phosphatidylcholine (PC), phosphatidylethanolamine (...

Background/Objectives: This study describes body composition, bone mineral density (BMD), and dietary intake in pediatric patients undergoing allogeneic hematopoietic stem cell transplantation compared to healthy children. Methods: In this prospectiv...

Background/Objectives: The nutrition transition in low- and middle-income countries has produced a double burden of malnutrition (coexistence of excess weight, undernutrition, and micronutrient deficiencies), with scarce evidence in schoolchildren fr...

Background/Objectives: Oligofructans are a category of non-digestible carbohydrates with beneficial effects on gut health and microbiota modulation. In this study, oligofructans were produced from raw sugar using Bacillus subtilis TISTR 001, and thei...

Background/Objectives: Ceratonia siliqua L. (carob) is a rich source of bioactive compounds with potential health-promoting properties. This study investigated the kinetics of serum metabolites following the consumption of a carob beverage and e...

Background/Objectives: Fortified eggs have been proposed as food-based vehicles for delivering micronutrients and other bioactive compounds. However, human intervention evidence remains fragmented across nutrient targets, populations, intervention de...

Background: Childhood dyslipidemia often tracks into adulthood and contributes to early atherosclerotic changes. Although serum 25-Hydroxyvitamin D (25(OH)D) has been implicated in lipid metabolism, findings in children remain inconsistent, and wheth...

Background: To investigate the diagnostic value of the SPT-to-histamine ratio, casein-specific immunoglobulin E (IgE), and cow’s milk-specific IgE in predicting oral food challenge (OFC) positivity in children with suspected cow’s milk al...

Background/Objectives: Pregnant women with obesity may experience a substantial burden of sleep disruption and obstetric risk, but prospective data integrating non-respiratory sleep symptoms, prescribed nutritional supplement exposure, and routinely...

This narrative review examines perimenopause as a critical transitional phase in women’s lives, often accompanied by elevated vulnerability to anxiety and depression. Dysfunction of the gut–brain axis is one of the key factors contributin...

Background: Endometriosis is a chronic, estrogen-dependent inflammatory disorder associated with pain and immune dysregulation. Omega-3 (n-3) fatty acids and fish-derived bioactive lipids may modulate inflammation and metabolism. This study investiga...

Background: Eating behaviors and psychological processes related to food consumption are increasingly recognized as key factors of successful adherence to a healthy dietary pattern. In this context, mindful eating and adherence to the Mediterranean D...

Background: Impaired insulin secretion by pancreatic beta cells drives chronic hyperglycemia, which characterizes type 2 diabetes mellitus. The mechanosensitive ion channel Piezo2 has been implicated in various physiological processes. However, its e...

Background: German chamomile (Matricaria chamomilla L.) and Roman chamomile (Chamaemelum nobile (L.) All.) are widely consumed botanical materials increasingly used in nutraceuticals and functional foods. Although both are marketed as “chamomil...

Background: Binge eating (BE) is frequently associated with negative emotional states, obesity, and physical inactivity. Although yoga may improve binge eating and emotional symptoms, its effects on physical fitness remain unclear. In contrast, high-...

Background: Several studies reveal an inverse relation between serum 25-hydroxyvitamin D [25(OH)D] concentration and the risk of acute ischemic stroke (AIS). The aim of this study was to determine relationships between 25(OH)D concentration and the c...

Background/Objectives: Cow’s milk protein allergy (CMPA), one of the most common allergies in early life, can present psychological, financial, and social challenges for caregivers. For mothers, this burden may be compounded by the fact that ex...

Introduction: Breast milk is the best food for a growing infant during the first 6 months of life. The presence of trans fatty acids (TFAs) in breast milk can interfere with the synthesis of long-chain polyunsaturated fatty acids (LC-PUFAs), increasi...