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Clinics and Practice, Volume 16, Issue 1

2026 January - 22 articles

Cover Story: Cement augmentation of cephalomedullary head elements is used to improve fixation in osteoporotic trochanteric fractures, but it does not remove the need for accurate positioning and preserved sliding. This cover highlights a rare failure: a post-union subcapital femoral neck fracture around a cement-augmented helical blade. Despite acceptable initial metrics, sliding remained constrained and progressive varus displacement developed, redirecting load to the subcapital region rather than dissipating it through telescoping. Serial radiographs with complementary CT/MRI suggest that excessive construct stiffness can shift stress after union. We propose a position- and sliding-based guide to flag early warning signs—pain, progressive varus, and lack of sliding progression—and to prompt consideration of conversion to arthroplasty. View this paper
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Articles (22)

  • Article
  • Open Access
1,022 Views
16 Pages

Fatigue Among Caregivers of Hospitalized Patients

  • Eleni Maria Mitrou,
  • Lamprini Avramopoulou,
  • Dimitrios Alefragkis,
  • Athanasia Tsami and
  • Maria Polikandrioti

Introduction: Caregiving has been an emerging public health priority mainly due to the rapid pace of population aging, increase in chronic diseases and shortages of health professionals. In clinical settings, caregivers have a crucial role by providi...

  • Review
  • Open Access
3 Citations
1,506 Views
10 Pages

Elderspeak is a form of communication overaccommodation directed toward older adults, characterized by simplified language and an elevated pitch. While typically well-intentioned, it is rooted in ageist stereotypes and linked to negative health outco...

  • Case Report
  • Open Access
703 Views
8 Pages

Primary Uterine NUT Carcinoma: A Case Report and Literature Review

  • Tetsuro Shiraishi,
  • Iori Kisu,
  • Naomi Kaneko,
  • Takaaki Fukuda,
  • Jun Watanabe,
  • Ryoma Hayashi,
  • Akihisa Ueno,
  • Katsura Emoto,
  • Kanako Nakamura and
  • Wataru Yamagami
  • + 3 authors

Background: Nuclear protein in testis (NUT) carcinoma is a rare, aggressive, and poorly differentiated epithelial malignancy characterized by the rearrangement of NUTM1 (NUT midline carcinoma family member 1) on 15q14. It primarily originates along t...

  • Case Report
  • Open Access
1 Citations
3,222 Views
7 Pages

A Hypersexuality Subset Behavior Induced by Aripiprazole Overdose in an Antipsychotic Naïve Patient: A Case Report and Review of the Literature

  • Tiziano Serfilippi,
  • Silvia Piccirillo,
  • Alessandra Preziuso,
  • Valentina Terenzi,
  • Francesca Romagnoli,
  • Marella Tarini,
  • Vincenzo Lariccia,
  • Agnese Secondo and
  • Simona Magi

Background: Aripiprazole is an atypical antipsychotic that acts as a partial agonist on the dopamine receptor D2 while also displaying agonistic activity on the 5-HT1A and antagonistic activity on the 5-HT2A receptors. As a partial agonist, aripipraz...

  • Article
  • Open Access
797 Views
15 Pages

Anxiety and Depression in Patients with Colorectal Cancer Undergoing Ileostomy

  • Panagiota Makrygianni,
  • Maria Polikandrioti,
  • Ioannis Koutelekos,
  • Ilias Tsiampouris and
  • Georgios Vasilopoulos

Introduction: Patients with colorectal cancer who undergo ileostomy surgery confront multifaceted challenges that significantly impact their daily lives and cause symptoms of anxiety and depression. The aim of this study was to explore the anxiety an...

  • Article
  • Open Access
662 Views
14 Pages

Background: Cardiac amyloidosis is characterized by progressive myocardial and atrial infiltration, leading to atrial mechanical dysfunction, atrial fibrillation, and thromboembolic complications. Left atrial (LA) strain is an established marker of a...

  • Article
  • Open Access
1 Citations
1,183 Views
13 Pages

Effectiveness of Group Voice Therapy in Teachers with Hyperfunctional Voice Disorder

  • Nataša Prebil,
  • Rozalija Kušar,
  • Maja Šereg Bahar and
  • Irena Hočevar Boltežar

Background/Objectives: The aim of this study was to assess the short-term and long-term effectiveness of group voice therapy in changing vocal behaviour and improving voice quality (VQ) among teachers with hyperfunctional voice disorders (HFVD), usin...

  • Systematic Review
  • Open Access
1 Citations
1,970 Views
16 Pages

A Systematic Review of Personality Disorders in Patients with Gambling Disorder

  • Ioana Ioniță,
  • Mădălina Iuliana Mușat,
  • Bogdan Cătălin,
  • Constantin Alexandru Ciobanu and
  • Adela Magdalena Ciobanu

Background/Objectives: Gambling disorder (GD) is characterized by a high prevalence of co-occurring psychiatric disorders, including personality disorders (PDs), which may negatively influence clinical presentation, treatment outcomes, and relapse ra...

  • Review
  • Open Access
2,632 Views
30 Pages

Telehealth for Sexual and Reproductive Healthcare: Evidence Map of Effectiveness, Patient and Provider Experiences and Preferences, and Patient Engagement Strategies

  • Romil R. Parikh,
  • Nishka U. Shetty,
  • Chinar Singhal,
  • Prachi Patel,
  • Priyanka Manghani,
  • Ashwin A. Pillai,
  • Luz Angela Chocontá-Piraquive and
  • Mary E. Butler

Objective: The aim of this study was to systematically map evidence to inform best practices for sexual and reproductive healthcare delivered via telehealth (TeleSRH) in United States-based Title X-funded clinics. Methods: We searched three databases...

  • Case Report
  • Open Access
1 Citations
784 Views
12 Pages

Ventricular Asystole During Le Fort I Orthognathic Surgery: A Case Consistent with Trigeminocardiac Reflex and a Mini Review

  • Sucharu Ghosh,
  • Sandra Armanious,
  • Anirudh Nair,
  • Zeynep Ulku,
  • Daniel Sultan and
  • Robert Pellecchia

Introduction: The trigeminocardiac reflex (TCR) is a brainstem reflex in which trigeminal stimulation precipitates abrupt vagally mediated cardiovascular changes, ranging from bradycardia to asystole. While classically described during down-fracture...

  • Article
  • Open Access
1,154 Views
25 Pages

Early Trajectories of Suicidality in Adolescents and Young Adults: A Retrospective Study from a Community Mental Health Facility in Northern Italy

  • Miriam Olivola,
  • Serena Chiara Civardi,
  • Silvia Carnevali,
  • Roberta Anniverno,
  • Federico Durbano and
  • Bernardo Maria Dell’Osso

Background/Objectives: Suicide is the second leading cause of death among adolescents and young adults. Those suffering from psychiatric illnesses are at particular risk. Our study, conducted at an outpatient mental health facility in Northern Italy,...

  • Article
  • Open Access
1,829 Views
27 Pages

Rotator Cuff-Related Shoulder Pain: A Survey of Current Physiotherapy Practice in Cyprus

  • George M. Pamboris,
  • Spyridon Plakias,
  • Charalambos Papacharalambous,
  • Kyriakos Pavlou,
  • Andrew Smythe,
  • Anna Christakou and
  • Eleftherios Paraskevopoulos

Background: Rotator cuff-related shoulder pain (RCRSP) is a prevalent musculoskeletal disorder treated by physiotherapists. Although international guidelines support active, exercise-based management, little is known about current physiotherapy pract...

  • Reply
  • Open Access
351 Views
2 Pages

Reply to Harsanyi et al. Comment on “Hasan et al. Clinico-Pathological Features and Immunohistochemical Comparison of p16, p53, and Ki-67 Expression in Muscle-Invasive and Non-Muscle-Invasive Conventional Urothelial Bladder Carcinoma. Clin. Pract. 2023, 13, 806–819”

  • Abdulkarim Hasan,
  • Yasien Mohammed,
  • Mostafa Basiony,
  • Mehenaz Hanbazazh,
  • Abdulhadi Samman,
  • Mohamed Fayek Abdelaleem,
  • Mohamed Nasr,
  • Hesham Abozeid,
  • Hassan Ismail Mohamed and
  • Essam Mandour
  • + 10 authors

We would like to thank Harsanyi et al [...]

  • Comment
  • Open Access
2 Citations
385 Views
2 Pages

We read with great interest the article Clinico-Pathological Features and Immunohistochemical Comparison of p16, p53, and Ki-67 Expression in Muscle-Invasive and Non-Muscle-Invasive Conventional Urothelial Bladder Carcinoma by Hasan et al [...]

  • Article
  • Open Access
1,741 Views
15 Pages

Background: Potential drug–drug interactions (pDDIs) present substantial challenges to medication safety during care transitions. Warfarin, with its narrow therapeutic index and extensive interaction profile, provides a strategic model for exam...

  • Article
  • Open Access
1,248 Views
12 Pages

Age- and Risk-Based Stratification in Dyspepsia: Redefining Endoscopic Thresholds for Clinically Significant and Malignant Findings

  • Oren Gal,
  • Dorin Nicola,
  • Amir Mari,
  • Randa Natour,
  • Noor Fanadka,
  • Ahlam Bsoul,
  • Ahmad Mahamid,
  • Rawi Hazzan and
  • Fadi Abu Baker

Background: Dyspepsia is a common indication for gastroscopy, yet its diagnostic yield for malignancy and other clinically significant findings (CSF) remains low. Improved risk stratification is therefore essential to guide endoscopic referral. This...

  • Systematic Review
  • Open Access
1 Citations
1,272 Views
17 Pages

Electrochemotherapy in the Management of Vascular Malformations: An Updated Systematic Review

  • Antonios Michailidis,
  • Ioannis Tsifountoudis,
  • Evangelos Perdikakis,
  • Georgios Fragkos,
  • Ola Furmaga-Rokou,
  • Prodromos Koutoukoglou,
  • Danae Makri,
  • Evangelos Petsatodis and
  • Stefanos Finitsis

Background: Vascular malformations (VMs) are congenital anomalies of the vascular system—capillary, venous, lymphatic, arteriovenous, or combined—frequently associated with notable morbidity and reduced quality of life. Electrochemotherap...

  • Article
  • Open Access
1,744 Views
16 Pages

Background: Clinical pharmacists are increasingly demonstrating their value within primary care; this process directly improves patient experiences and outcomes. However, many undergraduate pharmacy students have little or no experience in this area,...

  • Article
  • Open Access
1 Citations
1,021 Views
20 Pages

Patterns of Ocular Involvement and Associated Factors in Adult Measles: A Retrospective Study from a Romanian Tertiary Hospital

  • Dragoș Ștefan Lazăr,
  • Adina-Alexandra Nanu,
  • Ilie-Andrei Condurache,
  • Maria Nica,
  • Catrinel Tudosie,
  • Maria Alexandra Malciolu-Nica,
  • Alexandra Ioana Grigore,
  • George Sebastian Gherlan,
  • Corneliu Petru Popescu and
  • Simin Aysel Florescu

Background: Measles re-emergence has been reported across Europe, with Romania being among the most affected countries in 2023–2024. Although ocular manifestations are recognized in measles, their frequency and inflammatory correlates in hospit...

  • Article
  • Open Access
1 Citations
1,902 Views
35 Pages

Aim: To propose a standardized clinical protocol for cone-specific neuromodulation that classifies therapeutic filters for selective stimulation of S-, M-, and L-cones and translates optical and safety parameters into condition-specific frameworks fo...

  • Article
  • Open Access
539 Views
12 Pages

Quality of Online Information on Patient-Specific Knee Arthroplasty and Its Impact on Personalized Care

  • Patrick F. Marko,
  • Lukas K. Kriechbaumer,
  • Marian Mitterer and
  • Sebastian Filipp

Background: Patient-specific instrumentation (PSI) in total knee arthroplasty represents an increasingly relevant component of personalized surgical planning. As nearly half of orthopedic patients search online for medical information before or after...

  • Case Report
  • Open Access
937 Views
13 Pages

Background/Objectives: Cement augmentation of cephalomedullary head elements can improve the purchase of osteoporotic bone; however, it does not eliminate the need for accurate implant positioning or the preservation of sliding. We report the case of...

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Clin. Pract. - ISSN 2039-7283