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Nutrients, Volume 14, Issue 9

2022 May-1 - 307 articles

Cover Story: This original article provides evidence for a possible protective effect of higher plasma caffeine levels on Alzheimer’s disease. Neuroprotective effects of caffeine have been suggested by experimental data, but studies in humans on consumption of coffee, the major source of caffeine in most populations, in relation to neurodegenerative diseases have yielded conflicting findings. More research is needed to assess the role of increasing plasma caffeine levels on neurodegenerative diseases. View this paper
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Articles (307)

  • Article
  • Open Access
6 Citations
3,617 Views
14 Pages

Carotenoid Profile in Maternal/Cord Plasma and Changes in Breast Milk along Lactation and Its Association with Dietary Intake: A Longitudinal Study in a Coastal City in Southern China

  • Xinyao Dai,
  • Huanhuan Yin,
  • Jing Zhang,
  • Fang Tian,
  • Xiaokun Cai,
  • Yingyi Mao,
  • Hanxiao Sun,
  • He Wang,
  • Xiang Li and
  • Yanrong Zhao
  • + 3 authors

9 May 2022

In this study, changes of carotenoids in breast milk were observed longitudinally for up to one year. Our study aimed to analyze the profile of carotenoids in breast milk and maternal/cord plasma and its correlation with dietary intake in Guangzhou....

  • Article
  • Open Access
17 Citations
6,628 Views
15 Pages

9 May 2022

(1) Background: The aim of this study was to evaluate the effectiveness of a three-component nutrition, sleep, and physical activity (PA) program on cardiorespiratory fitness, body composition, and health behaviors in overweight airline pilots. (2) M...

  • Article
  • Open Access
23 Citations
4,779 Views
18 Pages

Dioscin Ameliorates Hyperuricemia-Induced Atherosclerosis by Modulating of Cholesterol Metabolism through FXR-Signaling Pathway

  • Ruixia Bao,
  • Wei Wang,
  • Beibei Chen,
  • Jujie Pan,
  • Qian Chen,
  • Mengyang Liu,
  • Dan Wang,
  • Yuzheng Wu,
  • Haiyang Yu and
  • Tao Wang
  • + 2 authors

9 May 2022

Hyperuricemia is one of the independent risk factors for atherosclerotic cardiovascular disease. Herein, we investigate the association between uric acid and cholesterol metabolism and the effect of dioscin on the prevention of hyperuricemia-induced...

  • Review
  • Open Access
117 Citations
21,555 Views
15 Pages

9 May 2022

L-serine plays an essential role in a broad range of cellular functions including protein synthesis, neurotransmission, and folate and methionine cycles and synthesis of sphingolipids, phospholipids, and sulphur containing amino acids. A hydroxyl sid...

  • Article
  • Open Access
7 Citations
4,483 Views
15 Pages

Alterations in Bacterial Metabolism Contribute to the Lifespan Extension Exerted by Guarana in Caenorhabditis elegans

  • Inés Reigada,
  • Karmen Kapp,
  • Claire Maynard,
  • David Weinkove,
  • Marta Sofía Valero,
  • Elisa Langa,
  • Leena Hanski and
  • Carlota Gómez-Rincón

9 May 2022

Guarana (Paullinia cupana) is a widely consumed nutraceutical with various health benefits supported by scientific evidence. However, its indirect health impacts through the gut microbiota have not been studied. Caenorhabditis elegans is a useful mod...

  • Article
  • Open Access
31 Citations
8,828 Views
13 Pages

9 May 2022

During their lifetime, 20% of US women experience depression. Studies have indicated that a high Dietary Inflammatory Index (DII) score is associated with high C-reactive protein (CRP) levels and depression. No previous study has compared the associa...

  • Review
  • Open Access
56 Citations
12,644 Views
13 Pages

Nutraceuticals/Drugs Promoting Mitophagy and Mitochondrial Biogenesis May Combat the Mitochondrial Dysfunction Driving Progression of Dry Age-Related Macular Degeneration

  • Lidianys María Lewis Luján,
  • Mark F. McCarty,
  • James J. Di Nicolantonio,
  • Juan Carlos Gálvez Ruiz,
  • Ema Carina Rosas-Burgos,
  • Maribel Plascencia-Jatomea and
  • Simon Bernard Iloki Assanga

9 May 2022

In patients with age-related macular degeneration (AMD), the crucial retinal pigment epithelial (RPE) cells are characterized by mitochondria that are structurally and functionally defective. Moreover, deficient expression of the mRNA-editing enzyme...

  • Article
  • Open Access
9 Citations
4,931 Views
10 Pages

9 May 2022

Dried ginger (Zingiberis Processum Rhizoma (ZR)) is frequently used to prevent or treat common cold and flu. This study aimed to investigate the influence of ZR extracts on influenza-specific antibody production in cyclophosphamide (Cy)-induced immun...

  • Systematic Review
  • Open Access
16 Citations
11,532 Views
21 Pages

n-3 PUFA Improve Emotion and Cognition during Menopause: A Systematic Review

  • Davide Decandia,
  • Eugenia Landolfo,
  • Stefano Sacchetti,
  • Francesca Gelfo,
  • Laura Petrosini and
  • Debora Cutuli

9 May 2022

Women show an increased risk of cognitive impairment and emotional disorders, such as anxiety and depression, when approaching menopause. Data on risk and protection factors have yielded robust evidence on the effects of lifestyle factors, such as di...

  • Article
  • Open Access
12 Citations
4,691 Views
14 Pages

Associations between Frequency of Culinary Herb Use and Gut Microbiota

  • Alexandra Adorno Vita,
  • Ryan McClure,
  • Yuliya Farris,
  • Robert Danczak,
  • Anders Gundersen,
  • Heather Zwickey and
  • Ryan Bradley

9 May 2022

While evidence suggests that culinary herbs have the potential to modulate gut microbiota, much of the current research investigating the interactions between diet and the human gut microbiome either largely excludes culinary herbs or does not assess...

  • Concept Paper
  • Open Access
9 Citations
4,525 Views
10 Pages

The Pre-Analytical CEN/TS Standard for Microbiome Diagnostics—How Can Research and Development Benefit?

  • Conny Stumptner,
  • Vanessa Stadlbauer,
  • Dominic O’Neil,
  • André Gessner,
  • Andreas Hiergeist,
  • Kurt Zatloukal and
  • Peter M. Abuja

9 May 2022

Recently, CEN/TS 17626:2021, the European pre-analytical standard for human specimens intended for microbiome DNA analysis, was published. Although this standard relates to diagnostic procedures for microbiome analysis and is relevant for in vitro di...

  • Article
  • Open Access
19 Citations
6,456 Views
13 Pages

Isatis tinctoria L. Leaf Extract Inhibits Replicative Senescence in Dermal Fibroblasts by Regulating mTOR-NF-κB-SASP Signaling

  • Jieun Woo,
  • Seoungwoo Shin,
  • Hyanggi Ji,
  • Dehun Ryu,
  • Eunae Cho,
  • Youngseok Kim,
  • Junoh Kim,
  • Deokhoon Park and
  • Eunsun Jung

9 May 2022

Senescent fibroblasts progressively deteriorate the functional properties of skin tissue. Senescent cells secrete senescence-associated secretory phenotype (SASP) factor, which causes the aging of surrounding non-senescent cells and accelerates aging...

  • Communication
  • Open Access
16 Citations
4,556 Views
8 Pages

9 May 2022

We retrospectively reviewed serum 25-hydroxy vitamin D (25(OH)D) test results from an adult Korean population visiting local clinics and hospitals between July 2017 and December 2021 to gather recent information on the prevalence of vitamin D deficie...

  • Review
  • Open Access
200 Citations
9,962 Views
15 Pages

9 May 2022

Intestinal microbiota has its role as an important component of human physiology. It produces metabolites that module key functions to establish a symbiotic crosstalk with their host. Among them, short chain fatty acids (SCFAs), produced by intestina...

  • Article
  • Open Access
21 Citations
4,952 Views
16 Pages

9 May 2022

Rosa roxburghii Tratt. fruit juice (Cili) is used as a medicinal and edible resource in China due to its antioxidant and hypolipidemic potentials. The efficacy of Cili in protecting alcohol-induced liver injury and its underlying mechanism was invest...

  • Article
  • Open Access
25 Citations
6,550 Views
11 Pages

A High-Fat Diet Induces Muscle Mitochondrial Dysfunction and Impairs Swimming Capacity in Zebrafish: A New Model of Sarcopenic Obesity

  • Yun-Yi Zou,
  • Zhang-Lin Chen,
  • Chen-Chen Sun,
  • Dong Yang,
  • Zuo-Qiong Zhou,
  • Qin Xiao,
  • Xi-Yang Peng and
  • Chang-Fa Tang

9 May 2022

Obesity is a highly prevalent disease that can induce metabolic syndrome and is associated with a greater risk of muscular atrophy. Mitochondria play central roles in regulating the physiological metabolism of skeletal muscle; however, whether a decr...

  • Review
  • Open Access
38 Citations
6,453 Views
14 Pages

The Impact of Flavonols on Cardiovascular Risk

  • Joanna Popiolek-Kalisz and
  • Emilia Fornal

9 May 2022

Cardiovascular disease (CVD) is the leading cause of deaths globally. The main target for prevention of cardiovascular (CV) risk are lifestyle changes, including particular dietary recommendations, involving high intake of fruits and vegetables. Flav...

  • Article
  • Open Access
3 Citations
6,190 Views
10 Pages

9 May 2022

The thyroid of the fetus of a mother with Graves’ disease (GD) is affected by the transplacental passage of both antithyroid drugs (ATDs) and thyroid-stimulating hormone receptor antibodies (TRAb). Thyroid hormone imbalances are harmful for the...

  • Article
  • Open Access
3 Citations
5,176 Views
11 Pages

9 May 2022

Among the physiological changes occurring during pregnancy, the benefits of morning sickness, which is likely mediated by human chorionic gonadotropin (HCG) and induces serum ketone production, are unclear. We investigated the relationship between se...

  • Article
  • Open Access
15 Citations
4,725 Views
16 Pages

8 May 2022

Family is the most fundamental and proximal context for children, and children’s eating behavior occurs mostly in the home or together with family members. With this study, we aimed to evaluate the distribution of family food environment dimens...

  • Review
  • Open Access
84 Citations
17,140 Views
29 Pages

Poultry Meat and Eggs as an Alternative Source of n-3 Long-Chain Polyunsaturated Fatty Acids for Human Nutrition

  • Alice Cartoni Mancinelli,
  • Simona Mattioli,
  • Cornelia Twining,
  • Alessandro Dal Bosco,
  • Ann M. Donoghue,
  • Komala Arsi,
  • Elisa Angelucci,
  • Diletta Chiattelli and
  • Cesare Castellini

8 May 2022

The beneficial effects of n-3 long-chain polyunsaturated fatty acids (n-3 LC-PUFA) on human health are widely known. Humans are rather inefficient in synthesizing n-3 LC-PUFA; thus, these compounds should be supplemented in the diet. However, most We...

  • Article
  • Open Access
22 Citations
4,026 Views
14 Pages

Determinants of Acceptance of Weight Management Applications in Overweight and Obese Individuals: Using an Extended Unified Theory of Acceptance and Use of Technology Model

  • Alexander Bäuerle,
  • Anna-Lena Frewer,
  • Vanessa Rentrop,
  • Lynik Chantal Schüren,
  • Marco Niedergethmann,
  • Julia Lortz,
  • Eva-Maria Skoda and
  • Martin Teufel

8 May 2022

Overweight and obesity carry a tremendous burden in terms of physiological and psychological comorbidities. There is a great variety of weight management applications to support weight reduction, but a systematical analysis of individuals’ need...

  • Article
  • Open Access
24 Citations
4,640 Views
15 Pages

Bacillus amyloliquefaciens Enriched Camel Milk Attenuated Colitis Symptoms in Mice Model

  • Ashraf Khalifa,
  • Abdullah Sheikh and
  • Hairul Islam Mohamed Ibrahim

8 May 2022

Fermented camel’s milk has various health beneficial prebiotics and probiotics. This study aimed to evaluate the preventive efficacy of Bacillus amyloliquefaciens enriched camel milk (BEY) in 2-, 4- and 6-Trinitrobenzenesulfonic acid (TNBS)-ind...

  • Article
  • Open Access
6 Citations
5,282 Views
15 Pages

Children’s School-Day Nutrient Intake in Ontario: A Cross-Sectional Observational Study Comparing Students’ Packed Lunches from Two School Schedules

  • Lisa J. Neilson,
  • Lesley A. Macaskill,
  • Jonathan M. H. Luk,
  • Navreeti Sharma,
  • Marina I. Salvadori,
  • Jamie A. Seabrook and
  • Paula D. N. Dworatzek

8 May 2022

This study compared the caloric and nutrient values of packed lunch contents and consumption in the Balanced School Day (BSD) (two 20 min eating periods) versus the Traditional Schedule (TS) (one 20 min lunch). Foods consumed during school were asses...

  • Article
  • Open Access
13 Citations
5,547 Views
14 Pages

7 May 2022

Adolescents exposed to food and beverage advertisements (FBAs) typically low in nutrient density can be influenced in their food choices, eating behaviors, and health. This study examines the association between perceptions and trust of FBAs (key pre...

  • Article
  • Open Access
10 Citations
4,925 Views
13 Pages

7 May 2022

White-fleshed pitaya (Selenicereus undatus) and red-fleshed pitaya (Selenicereus costaricensis) are becoming increasingly popular because of their nutritional and medicinal benefits. However, in addition to their beneficial properties, allergy to pit...

  • Article
  • Open Access
41 Citations
5,446 Views
11 Pages

7 May 2022

Diet-induced obesity is one of the major causes of the development of metabolic disorders such as insulin resistance and nonalcoholic fatty liver disease (NAFLD). Recently, specific probiotic strains have been found to improve the symptoms of NAFLD....

  • Article
  • Open Access
10 Citations
4,773 Views
15 Pages

7 May 2022

Background and aims: Insights into the nature of gut adaptation after different diets enhance the understanding of how food modifications can be used to treat type 2 diabetes and obesity. The aim was to understand how diets, enriched in fat or carboh...

  • Article
  • Open Access
6 Citations
3,291 Views
13 Pages

Behavioral Health Risk Factors and Motivation to Change among Cardiovascular General Hospital Patients Aged 50 to 79 Years

  • Ulrike Siewert-Markus,
  • Sabina Ulbricht,
  • Beate Gaertner,
  • Birgit-Christiane Zyriax,
  • Marcus Dörr,
  • Stefanie Tobschall,
  • Sophie Baumann,
  • Ulrich John and
  • Jennis Freyer-Adam

7 May 2022

Little is known about the (co-)occurrence of smoking, alcohol at-risk drinking, physical inactivity and overweight, and the motivation to change these behavioral health risk factors (HRFs) in older general hospital patients with cardiovascular diseas...

  • Article
  • Open Access
28 Citations
6,646 Views
14 Pages

Comparison of the 24 h Dietary Recall of Two Consecutive Days, Two Non-Consecutive Days, Three Consecutive Days, and Three Non-Consecutive Days for Estimating Dietary Intake of Chinese Adult

  • Kun Huang,
  • Liyun Zhao,
  • Qiya Guo,
  • Dongmei Yu,
  • Yuxiang Yang,
  • Qiuye Cao,
  • Xiaolin Yuan,
  • Lahong Ju,
  • Shujuan Li and
  • Hongyun Fang
  • + 2 authors

7 May 2022

The specific forms of 24 h dietary recall used by national nutrition surveys differ, such as two non-consecutive days and three consecutive days. However, it is unclear which form of 24 h dietary recall is more accurate in the Chinese population. The...

  • Article
  • Open Access
6 Citations
3,471 Views
15 Pages

7 May 2022

This study investigates the ability of a maternal cafeteria diet during lactation to program brown adipose tissue (BAT) metabolic responses to an obesogenic diet re-exposure in the adult offspring after consuming a standard diet (SD). Nursing rats we...

  • Review
  • Open Access
83 Citations
15,159 Views
15 Pages

Alcohol, Drinking Pattern, and Chronic Disease

  • María Barbería-Latasa,
  • Alfredo Gea and
  • Miguel A. Martínez-González

7 May 2022

This review discusses the inconsistent recommendations on alcohol consumption and its association with chronic disease, highlighting the need for an evidence-based consensus. Alcohol is an addictive substance consumed worldwide, especially in Europea...

  • Article
  • Open Access
15 Citations
3,841 Views
13 Pages

Associations between Meat and Vegetable Intake, Cooking Methods, and Asthenozoospermia: A Hospital-Based Case–Control Study in China

  • Ya-Shu Liu,
  • Yi-Xiao Zhang,
  • Xiao-Bin Wang,
  • Qi-Jun Wu,
  • Fang-Hua Liu,
  • Bo-Chen Pan and
  • Yu-Hong Zhao

7 May 2022

Background: The role of meat and vegetable intake in the development of asthenozoospermia has been controversial, and the role of cooking methods for meat and vegetables in the association has yet to be determined. The present study aimed to illumina...

  • Article
  • Open Access
13 Citations
3,759 Views
16 Pages

Dietary and Food Consumption Patterns and Their Associated Factors in the Tibetan Plateau Population: Results from 73 Counties with Agriculture and Animal Husbandry in Tibet, China

  • Chang Kong,
  • Linsheng Yang,
  • Hongqiang Gong,
  • Li Wang,
  • Hairong Li,
  • Yonghua Li,
  • Binggan Wei,
  • Cangjue Nima,
  • Yangzong Deji and
  • Rujun Li
  • + 5 authors

7 May 2022

Dietary imbalances are an important cause of morbidity and mortality, both in China and globally. Abnormal element content in the natural environment and the unbalanced dietary structure of populations coexist in the Tibetan Plateau. This study analy...

  • Article
  • Open Access
16 Citations
3,578 Views
12 Pages

HM-Chromanone Ameliorates Hyperglycemia and Dyslipidemia in Type 2 Diabetic Mice

  • Jae Eun Park,
  • Jaemin Son,
  • Youngwan Seo and
  • Ji Sook Han

6 May 2022

The effects of (E)-5-hydroxy-7-methoxy-3-(2-hydroxybenzyl)-4-chromanone (HMC) on hyperglycemia and dyslipidemia were investigated in diabetic mice. Mice were separated into three groups: db/db, rosiglitazone and HMC. Blood glucose or glycosylated hem...

  • Systematic Review
  • Open Access
15 Citations
7,983 Views
18 Pages

Impact of Food-Based Weight Loss Interventions on Gut Microbiome in Individuals with Obesity: A Systematic Review

  • Aleisha Bliesner,
  • Jade Eccles-Smith,
  • Claire Bates,
  • Olivia Hayes,
  • Jet Yee Ho,
  • Catia Martins,
  • Helen Truby and
  • Marloes Dekker Nitert

6 May 2022

The observation that the gut microbiota is different in healthy weight as compared with the obese state has sparked interest in the possible modulation of the microbiota in response to weight change. This systematic review investigates the effect of...

  • Review
  • Open Access
101 Citations
24,849 Views
31 Pages

The Therapeutic Role of Ketogenic Diet in Neurological Disorders

  • Diana Pietrzak,
  • Kamila Kasperek,
  • Paweł Rękawek and
  • Iwona Piątkowska-Chmiel

6 May 2022

The ketogenic diet (KD) is a high-fat, low-carbohydrate and adequate-protein diet that has gained popularity in recent years in the context of neurological diseases (NDs). The complexity of the pathogenesis of these diseases means that effective form...

  • Review
  • Open Access
28 Citations
7,366 Views
16 Pages

Therapeutic Role of Carotenoids in Blood Cancer: Mechanistic Insights and Therapeutic Potential

  • Yaseen Hussain,
  • Abdullah,
  • Khalaf F. Alsharif,
  • Michael Aschner,
  • Abdulrahman Theyab,
  • Fazlullah Khan,
  • Luciano Saso and
  • Haroon Khan

6 May 2022

Blood cancers are characterized by pathological disorders causing uncontrolled hematological cell division. Various strategies were previously explored for the treatment of blood cancers, including chemotherapy, Car-T therapy, targeting chimeric anti...

  • Review
  • Open Access
22 Citations
8,099 Views
10 Pages

6 May 2022

Prader–Willi syndrome (PWS) is a complex genetic disorder which involves the endocrine and neurologic systems, metabolism, and behavior. The aim of this paper is to summarize current knowledge on dietary management and treatment of PWS and, in...

  • Article
  • Open Access
19 Citations
6,925 Views
17 Pages

Factors Affecting Dental Caries Experience in 12-Year-Olds, Based on Data from Two Polish Provinces

  • Kinga Andrysiak-Karmińska,
  • Alicja Hoffmann-Przybylska,
  • Piotr Przybylski,
  • Zuzanna Witkowska,
  • Ewa Walicka,
  • Maria Borysewicz-Lewicka,
  • Iwona Gregorczyk-Maga,
  • Mansur Rahnama,
  • Karolina Gerreth and
  • Justyna Opydo-Szymaczek

6 May 2022

(1) Background: Dental caries is a chronic disease that affects a child’s dentition from the first stages of life. Several factors contribute to the development of the disease, including an improper diet. This cross-sectional study aimed to ide...

  • Article
  • Open Access
7 Citations
3,590 Views
12 Pages

6 May 2022

Patients with chronic obstructive pulmonary disease (COPD) suffer from exercise intolerance, the sensation of dyspnea, and fatigue, which are the main reasons for limiting their physical activity. In addition to changes in the respiratory and circula...

  • Article
  • Open Access
14 Citations
4,336 Views
15 Pages

Antilipidemic and Hepatoprotective Effects of Ethanol Extract of Justicia spicigera in Streptozotocin Diabetic Rats

  • Marina Murillo-Villicaña,
  • Ruth Noriega-Cisneros,
  • Donovan J. Peña-Montes,
  • Maribel Huerta-Cervantes,
  • Asdrubal Aguilera-Méndez,
  • Christian Cortés-Rojo,
  • Rafael Salgado-Garciglia,
  • Rocío Montoya-Pérez,
  • Héctor Riveros-Rosas and
  • Alfredo Saavedra-Molina

6 May 2022

Oxidative stress is a factor that contributes to the development of complications in diabetes; however, its effects can be counteracted using exogenous antioxidants that are found in some plants, which is why people turn to traditional medicines in t...

  • Article
  • Open Access
35 Citations
5,992 Views
23 Pages

Diet Quality and Dietary Inflammatory Index in Dutch Inflammatory Bowel Disease and Irritable Bowel Syndrome Patients

  • Marlijne C. G. de Graaf,
  • Corinne E. G. M. Spooren,
  • Evelien M. B. Hendrix,
  • Martine A. M. Hesselink,
  • Edith J. M. Feskens,
  • Agnieszka Smolinska,
  • Daniel Keszthelyi,
  • Marieke J. Pierik,
  • Zlatan Mujagic and
  • Daisy M. A. E. Jonkers

6 May 2022

Inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS) share common culprit foods and potential pathophysiological factors. However, how diet may contribute to disease course and whether this differs between both entities is unclear. We...

  • Article
  • Open Access
10 Citations
6,196 Views
17 Pages

Longitudinal Nutritional Intakes in Italian Pregnant Women in Comparison with National Nutritional Guidelines

  • Fabrizia Lisso,
  • Maddalena Massari,
  • Micaela Gentilucci,
  • Chiara Novielli,
  • Silvia Corti,
  • Leonardo Nelva Stellio,
  • Roberta Milazzo,
  • Ersilia Troiano,
  • Ella Schaefer and
  • Chiara Mandò
  • + 1 author

5 May 2022

Background: Nutritional quality during pregnancy is crucial for mother and child health and their short/long-term outcomes. The aim of this study is to evaluate the adherence to nutritional recommendations in Italy during the three pregnancy trimeste...

  • Review
  • Open Access
17 Citations
9,879 Views
11 Pages

5 May 2022

Calcifediol (25-OH-vitamin D3) is the prohormone of the vitamin D endocrine system. It is used to prevent and treat vitamin D deficiency. Calcifediol, as well as cholecalciferol (vitamin D3), is efficient and safe in the general population, although...

  • Article
  • Open Access
9 Citations
3,941 Views
12 Pages

5 May 2022

Background: Early research showed weight gain in children during the COVID-19 pandemic. Objective: To compare changes in BMI z-score of children with overweight and obesity in a personalised lifestyle intervention before and during the pandemic. Meth...

  • Article
  • Open Access
4 Citations
5,814 Views
10 Pages

Vitamin B12 Levels, Substance Use Patterns and Clinical Characteristics among People with Severe Substance Use Disorders: A Cohort Study from Western Norway

  • Tesfaye Madebo,
  • Mitra Bemanian,
  • Jørn Henrik Vold,
  • Ranadip Chowdhury,
  • Christer Frode Aas,
  • Karl Trygve Druckrey-Fiskaaen,
  • Kjell Arne Johansson and
  • Lars Thore Fadnes

5 May 2022

People with severe substance use disorder (SUD) have a higher burden of micronutrient deficiency compared with the general population. The aim of this study was to investigate vitamin B12 status and risk factors of deficiency related to substance use...

  • Article
  • Open Access
33 Citations
4,126 Views
17 Pages

Novel Soy Peptide CBP: Stimulation of Osteoblast Differentiation via TβRI-p38-MAPK-Depending RUNX2 Activation

  • Kuaitian Wang,
  • Xiao Kong,
  • Mengdi Du,
  • Wei Yu,
  • Zhenhua Wang,
  • Bo Xu,
  • Jianrong Yang,
  • Jingru Xu,
  • Zhili Liu and
  • Jing Gan
  • + 1 author

5 May 2022

DEDEQIPSHPPR, the calcium-binding peptide (CBP) identified in soy yogurt, was proven to be a potential cofactor in osteoporosis prevention in our previous study, but the mechanism was unknown. In this study, the activity of alkaline phosphatase (ALP)...

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Nutrients - ISSN 2072-6643