Nutrients, Volume 17, Issue 20
2025 October-2 - 130 articles
Cover Story: In acute geriatric care, time is critical, and prognosis is often uncertain. Malnutrition, systemic inflammation, and impaired immunity silently interact, shaping outcomes in vulnerable older adults. This study introduces the C-reactive protein–albumin–lymphocyte (CALLY) index as a powerful, easy-to-use prognostic tool. In a cohort of 264 very old patients, a low CALLY index identified those at greatest risk of adverse outcomes, such as short-term mortality after hospitalization. By combining three routine laboratory parameters into a single, integrated score, the CALLY index reflects multidimensional vulnerability with remarkable simplicity. Its implementation could support earlier, targeted interventions—shifting the focus from reactive care to proactive, personalized geriatric medicine and promoting appropriate care decisions. View this paper - Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
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