Nutrients, Volume 17, Issue 21
2025 November-1 - 182 articles
Cover Story: This study compared the short-term bioavailability of vitamin C from raw fruits and vegetables, their freshly prepared juices, and supplements in a randomized crossover trial involving healthy adults. Each participant consumed equivalent doses of vitamin C from these sources, and plasma and urinary vitamin C levels, related metabolites, and antioxidant activity were monitored over 24 h. Plasma vitamin C peaked two hours after intake, with juice demonstrating the highest absorption efficiency and area under the curve. Metabolomic profiling indicated shifts in urinary metabolites, suggesting microbiome-related metabolic responses. Although all sources contributed antioxidant benefits, freshly prepared juices provided more efficient vitamin C uptake compared with whole foods or supplements. View this paper - Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
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