Molecular and Cellular Mechanisms of Cardiovascular Diseases

Dear Colleagues,

Cardiovascular diseases are a leading cause of death worldwide. The Special Issue “Molecular and Cellular Mechanisms of Cardiovascular Disease” will focus on the pathophysiology of cardiovascular disorders including, but not limited to, hypertension, diabetes, coronary artery disease, valvular heart disease, infective endocarditis, aortic dissection and aneurysms, heart failure, congenital and acquired cardiomyopathies, and cardiac tumors. This Special Issue will focus on the known and new signaling pathways involved in the large spectrum of cardiovascular diseases, affecting calcium homeostasis, mitochondria and energy metabolism, oxidative stress, inflammation, cardiac cell survival and apoptosis, autophagy and the extracellular matrix. In addition, the alteration of hormonal and neurohormonal signaling, including adrenergic systems, renin–angiotensin–aldosterone systems, and sex hormones, as well as the molecular and cellular mechanisms leading to gender differences in cardiovascular disease will be included in this Special Issue. This Special Issue aims to provide a better understanding of the molecular and cellular mechanisms that lead to cardiovascular disease that have not yet been fully elucidated. Furthermore, our aim is to gain a general overview of the known and new therapeutic approaches and drug targets in the field. Comprehensive reviews and original research (basic, translational, or clinical research), providing new insights into the molecular and cellular mechanisms leading to cardiovascular disease, including novel therapeutic approaches, are welcome.

Dr. Antonella Galeone
Dr. Giacomina Brunetti
Guest Editors

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