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Diagnostics, Volume 13, Issue 24

2023 December-2 - 92 articles

Cover Story: Accurately predicting stroke recovery outcomes, measured by the modified Rankin Scale (mRS), from brain CT scans remains challenging yet clinically valuable. We tested deep learning models to predict a patient's mRS at 3 months post-stroke. We experimented with image-only models that make predictions directly from CT scans, and hybrid models that incorporate clinical and demographic information along with imaging data. In the hybrid models, we first extracted quantitative imaging biomarkers reflective of stroke damage from CT scans using deep learning. These imaging features were then incorporated into prognostic machine learning models for making outcome predictions. This approach could help address the challenges faced by image-only approach and also make the resulting model more interpretable. View this paper
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Articles (92)

  • Article
  • Open Access
3 Citations
3,581 Views
14 Pages

18 December 2023

Lung cancer (LC) stands as the foremost cause of cancer-related fatality rates worldwide. Early diagnosis significantly enhances patient survival rate. Nowadays, low-dose computed tomography (LDCT) is widely employed on the chest as a tool for large-...

  • Review
  • Open Access
32 Citations
12,366 Views
12 Pages

Clinical Diagnosis and Treatment of Chronic Pain

  • Sadiq Rahman,
  • Ali Kidwai,
  • Emiliya Rakhamimova,
  • Murad Elias,
  • William Caldwell and
  • Sergio D. Bergese

18 December 2023

More than 600 million people globally are estimated to be living with chronic pain. It is one of the most common complaints seen in an outpatient setting, with over half of patients complaining of pain during a visit. Failure to properly diagnose and...

  • Article
  • Open Access
1 Citations
2,284 Views
12 Pages

Performance Evaluation of Three Antibody Binding Assays, a Neutralizing Antibody Assay, and an Interferon-Gamma Release Assay for SARS-CoV-2 According to Vaccine Type in Vaccinated Group

  • Minjeong Nam,
  • Jae Hyun Cha,
  • Sang-Wook Kim,
  • Sun Bean Kim,
  • Ki-Byung Lee,
  • You-Seung Chung,
  • Seung Gyu Yun,
  • Myung-Hyun Nam,
  • Chang Kyu Lee and
  • Yunjung Cho

18 December 2023

We evaluated the performance of SARS-CoV-2 assays in the vaccinated group using receptor-binding domain antibody assays (RBD Ab assay), neutralizing antibody assay (nAb assay), and interferon-gamma release assay (IGR assay). We also compared the perf...

  • Article
  • Open Access
2,001 Views
14 Pages

18 December 2023

Purpose: To analyse the correspondence between refractive astigmatism and corneal astigmatism in pseudophakic eyes with non-toric intraocular lenses. Setting: Yeouido St. Mary hospital, Seoul, Republic of Korea. Design: Evaluation of a diagnostic tes...

  • Brief Report
  • Open Access
2 Citations
2,542 Views
10 Pages

Performance of a Point-of-Care Fluorescence Immunoassay Test to Measure the Anti-Severe Acute Respiratory Syndrome Corona Virus 2 Spike, Receptor Binding Domain Antibody Level

  • Marita Restie Tiara,
  • Hofiya Djauhari,
  • Febi Ramdhani Rachman,
  • Antonius Christianus Rettob,
  • Darmastuti Utami,
  • Fahda Cintia Suci Pulungan,
  • Heru Purwanta,
  • Rudi Wisaksana,
  • Bachti Alisjahbana and
  • Agnes Rengga Indrati

18 December 2023

Quantitative determination of anti-SARS-CoV2-S-RBD is necessary for the evaluation of vaccination effectiveness. The surrogate viral neutralization test (SVNT) is approved for measuring anti-SARS-CoV2-S-RBD, but a point-of-care platform is needed to...

  • Article
  • Open Access
5 Citations
3,930 Views
13 Pages

18 December 2023

Nasopharyngeal carcinoma (NPC) is an epithelial cancer originating in the nasopharynx epithelium. Nevertheless, annotating pathology slides remains a bottleneck in the development of AI-driven pathology models and applications. In the present study,...

  • Brief Report
  • Open Access
1 Citations
4,325 Views
9 Pages

The Histology-Driven Differential Diagnosis in Bowel Inflammatory Conditions Is Not All That Obvious: Evidence from a Survey Based on Digital Slides

  • Gabriella Canavese,
  • Enrico Costantino Falco,
  • Nuria Perez-Diaz-del-Campo,
  • Gian Paolo Caviglia,
  • Fabrizia Di Giovanni and
  • Davide Giuseppe Ribaldone

18 December 2023

(1) Background: when the pathologist faces histologic slides from colonoscopies in daily practice, given the large number of entities and etiologies under inflammatory bowel conditions, in-depth definition of the histological spectrum and the recomme...

  • Article
  • Open Access
4 Citations
3,091 Views
12 Pages

ECMO in Myocardial Infarction-Associated Cardiogenic Shock: Blood Biomarkers as Predictors of Mortality

  • Thomas Senoner,
  • Benedikt Treml,
  • Robert Breitkopf,
  • Ulvi Cenk Oezpeker,
  • Nicole Innerhofer,
  • Christine Eckhardt,
  • Aleksandra Radovanovic Spurnic and
  • Sasa Rajsic

17 December 2023

Background: Veno-arterial extracorporeal membrane oxygenation (va-ECMO) can provide circulatory and respiratory support in patients with cardiogenic shock. The main aim of this work was to investigate the association of blood biomarkers with mortalit...

  • Systematic Review
  • Open Access
8 Citations
5,595 Views
12 Pages

Clinical Validity of Anti-Proteinase 3 Antibodies in Patients with Inflammatory Bowel Disease: A Short Meta-Analysis

  • Carmen Andalucía,
  • Laura Martínez-Prat,
  • Chelsea Bentow,
  • Mary Ann Aure,
  • Michael P. Horn and
  • Michael Mahler

16 December 2023

Anti-neutrophil cytoplasmic antibodies (ANCA) directed to proteinase 3 (PR3) represent highly established markers for patients with ANCA-associated vasculitis (AAV). PR3-ANCA have also demonstrated utility in the management of inflammatory bowel dise...

  • Article
  • Open Access
1 Citations
2,638 Views
13 Pages

Prehospital Targeting of 1-Year Mortality in Acute Chest Pain by Cardiac Biomarkers

  • Daniel Zalama-Sánchez,
  • Francisco Martín-Rodríguez,
  • Raúl López-Izquierdo,
  • Juan F. Delgado Benito,
  • Irene Sánchez Soberón,
  • Carlos del Pozo Vegas and
  • Ancor Sanz-García

16 December 2023

The identification and appropriate management of patients at risk of suffering from acute chest pain (ACP) in prehospital care are not straightforward. This task could benefit, as occurs in emergency departments (EDs), from cardiac enzyme assessment....

  • Review
  • Open Access
8 Citations
6,081 Views
18 Pages

Evolution of Systemic Therapy in Medulloblastoma Including Irradiation-Sparing Approaches

  • Naureen Mushtaq,
  • Rahat Ul Ain,
  • Syed Ahmer Hamid and
  • Eric Bouffet

16 December 2023

The management of medulloblastoma in children has dramatically changed over the past four decades, with the development of chemotherapy protocols aiming at improving survival and reducing long-term toxicities of high-dose craniospinal radiotherapy. W...

  • Article
  • Open Access
8 Citations
6,298 Views
13 Pages

Whole Brain and Corpus Callosum Fractional Anisotropy Differences in Patients with Cognitive Impairment

  • Kalvis Kaļva,
  • Nauris Zdanovskis,
  • Kristīne Šneidere,
  • Andrejs Kostiks,
  • Guntis Karelis,
  • Ardis Platkājis and
  • Ainārs Stepens

16 December 2023

Diffusion tensor imaging (DTI) is an MRI analysis method that could help assess cognitive impairment (CI) in the ageing population more accurately. In this research, we evaluated fractional anisotropy (FA) of whole brain (WB) and corpus callosum (CC)...

  • Article
  • Open Access
5 Citations
3,235 Views
12 Pages

Development of Quality Indicators for the Ultrasound Department through a Modified Delphi Method

  • Aiping Zeng,
  • Yang Gu,
  • Li Ma,
  • Xixi Tao,
  • Luying Gao,
  • Jianchu Li,
  • Hongyan Wang and
  • Yuxin Jiang

15 December 2023

This study aims to establish precise quality indicators for evaluating and enhancing ultrasound performance, employing a methodology based on a comprehensive review of the literature, expert insights, and practical application experiences. We conduct...

  • Systematic Review
  • Open Access
80 Citations
12,801 Views
22 Pages

Artificial Intelligence and Its Clinical Applications in Orthodontics: A Systematic Review

  • Gianna Dipalma,
  • Alessio Danilo Inchingolo,
  • Angelo Michele Inchingolo,
  • Fabio Piras,
  • Vincenzo Carpentiere,
  • Grazia Garofoli,
  • Daniela Azzollini,
  • Merigrazia Campanelli,
  • Gregorio Paduanelli and
  • Francesco Inchingolo
  • + 1 author

15 December 2023

This review aims to analyze different strategies that make use of artificial intelligence to enhance diagnosis, treatment planning, and monitoring in orthodontics. Orthodontics has seen significant technological advancements with the introduction of...

  • Interesting Images
  • Open Access
4 Citations
4,932 Views
4 Pages

15 December 2023

Bitot’s spots (BS) are the buildup of superficially located keratin in the conjunctiva and are early indicators of vitamin A deficiency (VAD), primarily due to malnutrition and malabsorption, thus leading to xerophthalmia. BS are particularly p...

  • Article
  • Open Access
4 Citations
2,979 Views
13 Pages

Variety of Serotonin Levels in Pediatric Gastrointestinal Disorders

  • Loredana Matiș,
  • Lucia Georgeta Daina,
  • Lavinia Maris,
  • Timea Claudia Ghitea,
  • Daniela Florina Trifan,
  • Ioana Moga and
  • Radu Fodor

15 December 2023

(1) Serotonin primarily regulates our emotions. A complex process, which includes dysfunctions in gastrointestinal motility and deregulation of the gene responsible for serotonin reuptake (SERT), is implicated in the pathophysiology of irritable bowe...

  • Article
  • Open Access
2 Citations
2,173 Views
11 Pages

Cardiac Involvement in Classical Organic Acidurias: Clinical Profile and Outcome in a Pediatric Cohort

  • Silvia Passantino,
  • Serena Chiellino,
  • Francesca Girolami,
  • Mattia Zampieri,
  • Giovanni Battista Calabri,
  • Gaia Spaziani,
  • Elena Bennati,
  • Giulio Porcedda,
  • Elena Procopio and
  • Silvia Favilli
  • + 1 author

15 December 2023

Background: Cardiac involvement is reported in a significant proportion of patients with classical organic acidurias (OAs), contributing to disability and premature death. Different cardiac phenotypes have been described, among which dilated cardiomy...

  • Review
  • Open Access
12 Citations
4,702 Views
21 Pages

Advancing Colorectal Cancer Diagnosis with AI-Powered Breathomics: Navigating Challenges and Future Directions

  • Ioannis K. Gallos,
  • Dimitrios Tryfonopoulos,
  • Gidi Shani,
  • Angelos Amditis,
  • Hossam Haick and
  • Dimitra D. Dionysiou

15 December 2023

Early detection of colorectal cancer is crucial for improving outcomes and reducing mortality. While there is strong evidence of effectiveness, currently adopted screening methods present several shortcomings which negatively impact the detection of...

  • Article
  • Open Access
1 Citations
1,917 Views
20 Pages

Design and Simulate Intracranial Support to Guide Maxillo Surgery: A Study Based on Bioengineering

  • Maria Giulia Cristofaro,
  • Elvis Kallaverja,
  • Francesco Ferragina and
  • Ida Barca

14 December 2023

Background: Intraoperative navigation allows for the creation of a real-time relationship between the anatomy imagined during diagnosis/planning and the site of surgical interest. This procedure takes place by identifying and registering trustworthy...

  • Editorial
  • Open Access
6 Citations
4,403 Views
4 Pages

AI/ML-Based Medical Image Processing and Analysis

  • Jaafar Alghazo and
  • Ghazanfar Latif

14 December 2023

The medical field is experiencing remarkable advancements, notably with the latest technologies—artificial intelligence (AI), big data, high-performance computing (HPC), and high-throughput computing (HTC)—that are in place to offer groun...

  • Article
  • Open Access
28 Citations
4,453 Views
15 Pages

Computer-Aided Diagnosis of Laryngeal Cancer Based on Deep Learning with Laryngoscopic Images

  • Zhi-Hui Xu,
  • Da-Ge Fan,
  • Jian-Qiang Huang,
  • Jia-Wei Wang,
  • Yi Wang and
  • Yuan-Zhe Li

14 December 2023

Laryngeal cancer poses a significant global health burden, with late-stage diagnoses contributing to reduced survival rates. This study explores the application of deep convolutional neural networks (DCNNs), specifically the Densenet201 architecture,...

  • Article
  • Open Access
10 Citations
4,017 Views
18 Pages

The Challenge to Stabilize, Extract and Analyze Urinary Cell-Free DNA (ucfDNA) during Clinical Routine

  • Ivonne Nel,
  • Carolin Münch,
  • Saikal Shamkeeva,
  • Mitja L. Heinemann,
  • Berend Isermann and
  • Bahriye Aktas

14 December 2023

Background: The “Liquid Biopsy” has become a powerful tool for cancer research during the last decade. Circulating cell-free DNA (cfDNA) that originates from tumors has emerged as one of the most promising analytes. In contrast to plasma-...

  • Article
  • Open Access
5 Citations
3,183 Views
11 Pages

14 December 2023

The emergence of the Omicron (B.1.1.529) variant of SARS-CoV-2 has precipitated a new global wave of the COVID-19 pandemic. The rapid identification of SARS-CoV-2 infection is imperative for the effective mitigation of transmission. Diagnostic modali...

  • Article
  • Open Access
2 Citations
3,250 Views
17 Pages

Artificial Intelligence Image Recognition System for Preventing Wrong-Site Upper Limb Surgery

  • Yi-Chao Wu,
  • Chao-Yun Chang,
  • Yu-Tse Huang,
  • Sung-Yuan Chen,
  • Cheng-Hsuan Chen and
  • Hsuan-Kai Kao

14 December 2023

Our image recognition system employs a deep learning model to differentiate between the left and right upper limbs in images, allowing doctors to determine the correct surgical position. From the experimental results, it was found that the precision...

  • Review
  • Open Access
2 Citations
4,439 Views
17 Pages

Focus on Paediatric Restrictive Cardiomyopathy: Frequently Asked Questions

  • Mattia Zampieri,
  • Chiara Di Filippo,
  • Chiara Zocchi,
  • Vera Fico,
  • Cristina Golinelli,
  • Gaia Spaziani,
  • Giovanni Calabri,
  • Elena Bennati,
  • Francesca Girolami and
  • Silvia Favilli
  • + 7 authors

14 December 2023

Restrictive cardiomyopathy (RCM) is characterized by restrictive ventricular pathophysiology determined by increased myocardial stiffness. While suspicion of RCM is initially raised by clinical evaluation and supported by electrocardiographic and ech...

  • Article
  • Open Access
4 Citations
1,980 Views
12 Pages

Plasma 25-Hydroxyvitamin D and 1,25-Dihydroxyvitamin D Levels in Breast Cancer Risk in Mali: A Case–Control Study

  • Aboubacar D. T. Bissan,
  • Madani Ly,
  • Awo Emmanuela H. Amegonou,
  • Fatoumata M. Sidibe,
  • Bocary S. Koné,
  • Nènè Oumou K. Barry,
  • Madiné Tall,
  • Lassana G. Timbiné,
  • Bourèma Kouriba and
  • Zahra Ouzzif
  • + 1 author

14 December 2023

(1) Background: Breast cancer is the most prevalent cancer found in women in Mali. The aim of the current study was to determine the association between metabolites circulating in the blood, 25(OH)D and 1,25(OH)2D, and vitamin D levels with the risk...

  • Systematic Review
  • Open Access
15 Citations
4,520 Views
14 Pages

14 December 2023

Miniaturization has made ultrasound (US) technology ultraportable and, in association with their relatively low cost, made handheld devices attractive for medical education training programs. However, performing an ultrasound requires complex skills,...

  • Article
  • Open Access
10 Citations
2,605 Views
19 Pages

Rare Pancreatic/Peripancreatic Cystic Lesions Can Be Accurately Characterized by EUS with Through-the-Needle Biopsy—A Unique Pictorial Essay with Clinical and Histopathological Correlations

  • Maria Cristina Conti Bellocchi,
  • Erminia Manfrin,
  • Alessandro Brillo,
  • Laura Bernardoni,
  • Andrea Lisotti,
  • Pietro Fusaroli,
  • Alice Parisi,
  • Sokol Sina,
  • Antonio Facciorusso and
  • Stefano Francesco Crinò
  • + 1 author

14 December 2023

Due to their aspecific macroscopic appearance, uncommon pancreatic cystic lesions (PCLs) are often misdiagnosed as mucinous lesions and improperly resected. We aimed to evaluate the endoscopic ultrasound (EUS)-guided through-the-needle biopsy (TTNB)...

  • Review
  • Open Access
19 Citations
13,003 Views
12 Pages

Diagnostic Significance of Tryptase for Suspected Mast Cell Disorders

  • Michiel Beyens,
  • Alessandro Toscano,
  • Didier Ebo,
  • Theo Gülen and
  • Vito Sabato

14 December 2023

Tryptase has proven to be a very useful and specific marker to demonstrate mast cell activation and degranulation when an acute (i.e., within 4 h after the event) and baseline value (i.e., at least 24 h after the event) are compared and meet the cons...

  • Article
  • Open Access
15 Citations
3,940 Views
13 Pages

Attenuation Correction of Long Axial Field-of-View Positron Emission Tomography Using Synthetic Computed Tomography Derived from the Emission Data: Application to Low-Count Studies and Multiple Tracers

  • Maria Elkjær Montgomery,
  • Flemming Littrup Andersen,
  • Sabrina Honoré d’Este,
  • Nanna Overbeck,
  • Per Karkov Cramon,
  • Ian Law,
  • Barbara Malene Fischer and
  • Claes Nøhr Ladefoged

14 December 2023

Recent advancements in PET/CT, including the emergence of long axial field-of-view (LAFOV) PET/CT scanners, have increased PET sensitivity substantially. Consequently, there has been a significant reduction in the required tracer activity, shifting t...

  • Interesting Images
  • Open Access
3 Citations
3,788 Views
11 Pages

Congenital High Airway Obstructive Syndrome (CHAOS) Survival of a Newborn with Laryngeal Atresia

  • Carmen Heriseanu,
  • Mihaela Bizubac,
  • Loredana Draghia,
  • Veronica Marcu,
  • Dan Gheorghe and
  • Catalin Cirstoveanu

14 December 2023

Congenital high airway obstructive syndrome (CHAOS) is a rare congenital anomaly, frequently caused by laryngeal or tracheal atresia, tracheal stenosis, and obstructing laryngeal cysts. This is a congenital malformation, often fatal, with an unknown...

  • Article
  • Open Access
2 Citations
2,406 Views
11 Pages

FcRn Expression in Endometrial Cancer and Its Association with Clinicopathologic Features

  • Dae Hyun Song,
  • Juseok Yang,
  • Cho Hee Kim,
  • Min Hye Kim,
  • Jae Yoon Jo and
  • Jong Chul Baek

14 December 2023

Background: Endometrial cancer (EC) has robust molecular diagnostic evidence that correlates well with prognosis. In various types of cancers, FcRn has been identified as an early marker for prognosis. This study aims to assess FcRn expression and it...

  • Review
  • Open Access
5 Citations
3,375 Views
20 Pages

Review on Pediatric Malignant Focal Liver Lesions with Imaging Evaluation: Part II

  • Yi Dong,
  • Andrius Cekuolis,
  • Dagmar Schreiber-Dietrich,
  • Rasa Augustiniene,
  • Simone Schwarz,
  • Kathleen Möller,
  • Nasenien Nourkami-Tutdibi,
  • Sheng Chen,
  • Jia-Ying Cao and
  • Christoph F. Dietrich
  • + 4 authors

14 December 2023

Malignant focal liver lesions (FLLs) represent various kinds of epithelial and mesenchymal tumors. In pediatric patients, the understanding of pediatric liver diseases and associated imaging manifestations is essential for making accurate diagnosis a...

  • Case Report
  • Open Access
2 Citations
3,137 Views
12 Pages

Metastatic Breast Cancer Presenting as Acute Appendicitis: A Rare Case Study and Review of Current Knowledge

  • Nenad Markovic,
  • Bojan Stojanovic,
  • Ivan Jovanovic,
  • Bojan Milosevic,
  • Marko Spasic,
  • Ivan Radosavljevic,
  • Natasa Zdravkovic,
  • Dragce Radovanovic,
  • Bojana S. Stojanovic and
  • Milica Dimitrijevic Stojanovic
  • + 6 authors

13 December 2023

This manuscript discusses a rare case of acute appendicitis caused by metastasis from invasive breast carcinoma of no special type in a 70-year-old female previously diagnosed with breast cancer. It delves into the diagnostic challenges and managemen...

  • Article
  • Open Access
5 Citations
7,510 Views
15 Pages

Low Vitamin D Levels Are Associated with Increased Cardiac Iron Uptake in Beta-Thalassemia Major

  • Antonella Meloni,
  • Laura Pistoia,
  • Cristina Vassalle,
  • Anna Spasiano,
  • Ilaria Fotzi,
  • Sergio Bagnato,
  • Maria Caterina Putti,
  • Antonella Cossu,
  • Francesco Massei and
  • Filippo Cademartiri
  • + 3 authors

13 December 2023

We evaluated the association of vitamin D and parathormone (PTH) levels with cardiac iron and function in beta-thalassemia major (β-TM) patients. Two-hundred and seventy-eight TM patients (39.04 ± 8.58 years, 56.8% females) underwent magn...

  • Article
  • Open Access
2 Citations
3,163 Views
12 Pages

13 December 2023

Currently, over 200,000 new cases of leprosy are reported annually worldwide. Although leprosy was thought to have been eradicated in Taiwan, a few new cases still occur annually. Protean clinical manifestations of leprosy and immunological reactions...

  • Article
  • Open Access
3,069 Views
15 Pages

Diffusion-Weighted MR Imaging of the Thymus in Children with Non-Thymic Neoplasms

  • Sook Min Hwang,
  • Ji Eun Park,
  • So-Young Yoo,
  • Ji Hye Kim,
  • Sun-Young Baek,
  • Sung-Hoon Moon and
  • Tae Yeon Jeon

13 December 2023

Purpose: To investigate the diffusion-weighted imaging (DWI) findings and apparent diffusion coefficient (ADC) value of the thymus in children under the age of 13 who have non-thymic neoplasms. Materials and Methods: From January 2021 to April 2023,...

  • Communication
  • Open Access
1,416 Views
13 Pages

Identification of Messenger RNA Signatures in Age-Dependent Renal Impairment

  • Katsunori Yanai,
  • Shohei Kaneko,
  • Akinori Aomatsu,
  • Keiji Hirai,
  • Susumu Ookawara and
  • Yoshiyuki Morishita

13 December 2023

In general populations, age-dependent renal impairment contributes to the progression of renal dysfunction. It has not been known which molecules are involved in age-dependent renal impairment. Messenger RNA (mRNA) has been reported to modulate vario...

  • Article
  • Open Access
2 Citations
2,301 Views
14 Pages

Prophylactic Medication during Radioembolization in Metastatic Liver Disease: Is It Really Necessary? A Retrospective Cohort Study and Systematic Review of the Literature

  • Manon N. G. J. A. Braat,
  • Sander C. Ebbers,
  • Ahmed A. Alsultan,
  • Atal O. Neek,
  • Rutger C. G. Bruijnen,
  • Maarten L. J. Smits,
  • Joep de Bruijne,
  • Marnix G. E. H. Lam and
  • Arthur J. A. T. Braat

12 December 2023

Purpose: Trans-arterial radioembolization is a well-studied tumoricidal treatment for liver malignancies; however, consensus and evidence regarding periprocedural prophylactic medication (PPM) are lacking. Methods: A single-center retrospective analy...

  • Article
  • Open Access
3 Citations
1,828 Views
10 Pages

12 December 2023

In this cross-sectional study, optical coherence tomography angiography (OCT-A) findings were compared in patients with gout (n = 30) and healthy participants (n = 32). The superficial and deep vessel density variables measured using OCT-A were compa...

  • Review
  • Open Access
2 Citations
5,396 Views
16 Pages

12 December 2023

Testosterone (T), the principal androgen secreted by the testes, plays an essential role in male health. Male hypogonadism is diagnosed based on a combination of associated clinical signs and symptoms and laboratory confirmation of low circulating T...

  • Review
  • Open Access
62 Citations
36,493 Views
28 Pages

12 December 2023

Dental caries remains a significant global health issue. It was highlighted by the World Health Organization’s 2022 reports that despite the efforts and scientific advancements in caries detection and management, the situation has only marginal...

  • Article
  • Open Access
6 Citations
4,438 Views
14 Pages

Total Antioxidant Capacity of Saliva and Its Correlation with pH Levels among Dental Students under Different Stressful Conditions

  • Christoph Schwarz,
  • Octavia Balean,
  • Ramona Dumitrescu,
  • Paula Diana Ciordas,
  • Catalin Marian,
  • Marius Georgescu,
  • Vanessa Bolchis,
  • Ruxandra Sava-Rosianu,
  • Aurora Doris Fratila and
  • Atena Galuscan
  • + 2 authors

12 December 2023

(1) Background: This cross-sectional study conducted at the Faculty of Dental Medicine, Timisoara, Romania, between December 2022 and February 2023 aims to assess salivary total antioxidant capacity and pH levels in dental students experiencing non-s...

  • Brief Report
  • Open Access
3 Citations
3,286 Views
7 Pages

12 December 2023

Glucose-6-phosphate dehydrogenase (G6PD) deficiency is prevalent in the African American population. We identified eighteen G6PD-deficient samples (9%) in a study of residual, de-identified whole blood specimens from 200 African American pediatric pa...

  • Article
  • Open Access
4 Citations
2,268 Views
13 Pages

Ultrasound Entropy Imaging Based on the Kernel Density Estimation: A New Approach to Hepatic Steatosis Characterization

  • Ruiyang Gao,
  • Po-Hsiang Tsui,
  • Shuicai Wu,
  • Dar-In Tai,
  • Guangyu Bin and
  • Zhuhuang Zhou

12 December 2023

In this paper, we present the kernel density estimation (KDE)-based parallelized ultrasound entropy imaging and apply it for hepatic steatosis characterization. A KDE technique was used to estimate the probability density function (PDF) of ultrasound...

  • Article
  • Open Access
9 Citations
2,196 Views
12 Pages

An Intra-Individual Comparison of Low-keV Photon-Counting CT versus Energy-Integrating-Detector CT Angiography of the Aorta

  • Jan-Lucca Hennes,
  • Henner Huflage,
  • Jan-Peter Grunz,
  • Viktor Hartung,
  • Anne Marie Augustin,
  • Theresa Sophie Patzer,
  • Pauline Pannenbecker,
  • Bernhard Petritsch,
  • Thorsten Alexander Bley and
  • Philipp Gruschwitz

12 December 2023

This retrospective study aims to provide an intra-individual comparison of aortic CT angiographies (CTAs) using first-generation photon-counting-detector CT (PCD-CT) and third-generation energy-integrating-detector CT (EID-CT). High-pitch CTAs were p...

  • Article
  • Open Access
16 Citations
3,703 Views
13 Pages

The Development and Validation of an AI Diagnostic Model for Sacroiliitis: A Deep-Learning Approach

  • Kyu-Hong Lee,
  • Ro-Woon Lee,
  • Kyung-Hee Lee,
  • Won Park,
  • Seong-Ryul Kwon and
  • Mie-Jin Lim

12 December 2023

Purpose: Sacroiliitis refers to the inflammatory condition of the sacroiliac joints, frequently causing lower back pain. It is often associated with systemic conditions. However, its signs on radiographic images can be subtle, which may result in it...

  • Article
  • Open Access
2 Citations
2,725 Views
15 Pages

Characteristics of Pre-Lens Tear Film Behavior in Eyes Wearing Delefilcon A Silicone Hydrogel Water Gradient Contact Lenses

  • Norihiko Yokoi,
  • Yuki Furusawa,
  • Hiroaki Kato,
  • Natsuki Kusada,
  • Chie Sotozono,
  • Petar Eftimov and
  • Georgi As. Georgiev

12 December 2023

The pre-lens tear film (PLTF) over (i) delefilcon A silicone hydrogel water gradient (WG; 33–80% from core to surface) contact lenses (CLs) (SHWG-CLs) and (ii) subjects’ own non-WG soft CLs (SCLs) (SO-SCLs) was studied in 30 eyes of 30 su...

  • Interesting Images
  • Open Access
1 Citations
2,982 Views
4 Pages

Traumatic Anterior Cervical Disc Herniation Presenting as Severe Dysphagia

  • Jonghun Seo,
  • Jeonghyun Oh,
  • Pius Kim,
  • Chang Il Ju and
  • Seok Won Kim

12 December 2023

Due to the anatomical characteristics of the cervical spine, few cases of traumatic anterior cervical disc herniation have been reported in the literature. Here, we present a rare case of a traumatic anterior cervical disc herniation presenting as se...

  • Article
  • Open Access
14 Citations
2,300 Views
14 Pages

The Naples Prognostic Score Is a Useful Tool to Assess Surgical Treatment in Non-Small Cell Lung Cancer

  • Stefano Elia,
  • Alexandro Patirelis,
  • Georgia Hardavella,
  • Antonella Santone,
  • Federica Carlea and
  • Eugenio Pompeo

12 December 2023

Different prognostic scores have been applied to identify patients with non-small cell lung cancer who have a higher probability of poor outcomes. In this study, we evaluated whether the Naples Prognostic Score, a novel index that considers both infl...

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Diagnostics - ISSN 2075-4418