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  • Systematic Review
  • Open Access
745 Citations
210,950 Views
15 Pages

26 December 2023

The significant advancements in applying artificial intelligence (AI) to healthcare decision-making, medical diagnosis, and other domains have simultaneously raised concerns about the fairness and bias of AI systems. This is particularly critical in...

  • Article
  • Open Access
66 Citations
31,952 Views
22 Pages

LSTM–Transformer-Based Robust Hybrid Deep Learning Model for Financial Time Series Forecasting

  • Md R. Kabir,
  • Dipayan Bhadra,
  • Moinul Ridoy and
  • Mariofanna Milanova

10 January 2025

The inherent challenges of financial time series forecasting demand advanced modeling techniques for reliable predictions. Effective financial time series forecasting is crucial for financial risk management and the formulation of investment decision...

  • Review
  • Open Access
62 Citations
25,552 Views
26 Pages

15 December 2023

In recent years, generative transformers have become increasingly prevalent in the field of artificial intelligence, especially within the scope of natural language processing. This paper provides a comprehensive overview of these models, beginning w...

  • Review
  • Open Access
61 Citations
23,111 Views
16 Pages

30 October 2023

Blockchain offers a cutting-edge solution for storing medical data, carrying out medical transactions, and establishing trust for medical data integration and exchange in a decentralized open healthcare network setting. While blockchain in healthcare...

  • Review
  • Open Access
55 Citations
32,405 Views
24 Pages

Evolving Paradigms of Recombinant Protein Production in Pharmaceutical Industry: A Rigorous Review

  • Achuth Jayakrishnan,
  • Wan Rosalina Wan Rosli,
  • Ahmad Rashidi Mohd Tahir,
  • Fashli Syafiq Abd Razak,
  • Phei Er Kee,
  • Hui Suan Ng,
  • Yik-Ling Chew,
  • Siew-Keah Lee,
  • Mahenthiran Ramasamy and
  • Kai Bin Liew
  • + 1 author

31 January 2024

Many beneficial proteins have limited natural availability, which often restricts their supply and thereby reduces their potential for therapeutic or industrial usage. The advent of recombinant DNA (rDNA) technology enables the utilization of differe...

  • Review
  • Open Access
40 Citations
18,411 Views
37 Pages

9 April 2025

Microbial enzymes have revolutionised the textile industry by replacing harmful chemicals with eco-friendly alternatives, enhancing processes such as desizing, scouring, dyeing, finishing, and promoting water conservation while reducing pollution. Th...

  • Review
  • Open Access
38 Citations
34,606 Views
38 Pages

Challenges and Opportunities in the Implementation of AI in Manufacturing: A Bibliometric Analysis

  • Lorena Espina-Romero,
  • Humberto Gutiérrez Hurtado,
  • Doile Ríos Parra,
  • Rafael Alberto Vilchez Pirela,
  • Rosa Talavera-Aguirre and
  • Angélica Ochoa-Díaz

3 October 2024

This study explores the evolution and impact of research on the challenges and opportunities in the implementation of artificial intelligence (AI) in manufacturing between 2019 and August 2024. By addressing the growing integration of AI technologies...

  • Article
  • Open Access
36 Citations
2,783 Views
16 Pages

An Explainable Multi-Model Stacked Classifier Approach for Predicting Hepatitis C Drug Candidates

  • Teuku Rizky Noviandy,
  • Aga Maulana,
  • Ghifari Maulana Idroes,
  • Rivansyah Suhendra,
  • Razief Perucha Fauzie Afidh and
  • Rinaldi Idroes

6 December 2024

Hepatitis C virus (HCV) infection affects over 71 million people worldwide, leading to severe liver diseases, including cirrhosis and hepatocellular carcinoma. The virus’s high mutation rate complicates current antiviral therapies by promoting...

  • Concept Paper
  • Open Access
32 Citations
8,242 Views
16 Pages

Digital Twins in Manufacturing: A RAMI 4.0 Compliant Concept

  • Martin Lindner,
  • Lukas Bank,
  • Johannes Schilp and
  • Matthias Weigold

10 October 2023

Digital twins are among the technologies that are considered to have high potential. At the same time, there is no uniform understanding of what this technology means. Definitions are used across disciplinary boundaries, resulting in a multitude of d...

  • Article
  • Open Access
29 Citations
9,645 Views
12 Pages

2 April 2024

Audio classification using deep learning models, which is essential for applications like voice assistants and music analysis, faces challenges when deployed on edge devices due to their limited computational resources and memory. Achieving a balance...

  • Article
  • Open Access
22 Citations
4,156 Views
14 Pages

Non-Flammable Epoxy Composition Based on Epoxy Resin DER-331 and 4-(β-Carboxyethenyl)phenoxy-phenoxycyclotriphosphazenes with Increased Adhesion to Metals

  • Anastasia Konstantinova,
  • Pavel Yudaev,
  • Aleksey Shapagin,
  • Darya Panfilova,
  • Aleksandr Palamarchuk and
  • Evgeniy Chistyakov

23 May 2024

Functional cyclophosphazenes have proven to be effective modifiers of polymer materials, significantly improving their performance properties, such as adhesive characteristics, mechanical strength, thermal stability, fire resistance, etc. In this stu...

  • Review
  • Open Access
21 Citations
8,416 Views
27 Pages

A Review of the State of the Art for the Internet of Medical Things

  • Peter Matthew,
  • Sarah Mchale,
  • Xutao Deng,
  • Ghada Nakhla,
  • Marcello Trovati,
  • Nonso Nnamoko,
  • Ella Pereira,
  • Huaizhong Zhang and
  • Mohsin Raza

24 March 2025

The technological developments in the Internet of Things (IoT), data science, artificial intelligence, wearable sensors, remote monitoring, decision support systems, fog, and edge systems have transformed digital healthcare. Especially after the pand...

  • Review
  • Open Access
20 Citations
11,132 Views
21 Pages

4 February 2024

Petrochemical feedstocks are experiencing a fast growth in demand, which will further expand their market in the coming years. This is due to an increase in the demand for petrochemical-based materials that are used in households, hospitals, transpor...

  • Article
  • Open Access
19 Citations
8,103 Views
21 Pages

2 August 2024

This study investigates the potential health risks associated with consuming mussels (Mytilus galloprovincialis Lamarck, 1819) from the Romanian Black Sea coast between 2001 and 2023. The research focuses on heavy metal (copper, cadmium, lead, nickel...

  • Review
  • Open Access
19 Citations
10,415 Views
17 Pages

An Overview on Spheroid and Organoid Models in Applied Studies

  • Zorislava Živković and
  • Teuta Opačak-Bernardi

4 March 2025

From its inception, cell culture has been a great scientific tool for researchers in many diverse fields. The advancement from monolayer 2D cultures into three-dimensional cellular systems enabled a better experimental tool, as the 3D culture mimics...

  • Article
  • Open Access
15 Citations
11,775 Views
22 Pages

10 April 2025

Eye-gaze writing technology holds significant promise but faces several limitations. Existing eye-gaze-based systems often suffer from slow performance, particularly under challenging conditions such as low-light environments, user fatigue, or excess...

  • Review
  • Open Access
15 Citations
6,822 Views
40 Pages

Advancements of Biohydrogen Production Based on Anaerobic Digestion: Technologies, Substrates, and Future Prospects

  • Rossana Parra,
  • Cristhian Chicaiza-Ortiz,
  • Robinson J. Herrera-Feijoo,
  • Diana Victoria Arellano-Yasaca,
  • Lien-Chieh Lee,
  • Roberto Xavier Supe-Tulcan and
  • Jaime Marti-Herrero

29 April 2025

Population growth has significantly increased energy and resource demands, driving research toward cost-effective technologies that repurpose waste into alternative energy forms such as biohydrogen. This review aims to comprehensively evaluate biohyd...

  • Review
  • Open Access
15 Citations
41,018 Views
24 Pages

Recent Developments in Luteolin-Loaded Nanoformulations for Enhanced Anti-Carcinogenic Activities: Insights from In Vitro and In Vivo Studies

  • Muhammad Redza Fahmi Mod Razif,
  • Siok Yee Chan,
  • Yik-Ling Chew,
  • Masriana Hassan,
  • Shairyzah Ahmad Hisham,
  • Shamima Abdul Rahman,
  • Chun-Wai Mai,
  • Michelle Yee Mun Teo,
  • Phei Er Kee and
  • Kai Bin Liew
  • + 2 authors

25 October 2024

With approximately 18 million people affected by cancer in 2020 globally, scientists are exploring innovative approaches to develop effective treatments for various types of cancer. Traditional chemotherapy drugs, although effective against cancer ce...

  • Review
  • Open Access
14 Citations
11,059 Views
30 Pages

Anti-Aging Potential of Bioactive Phytoconstituents Found in Edible Medicinal Plants: A Review

  • Emeka Joshua Iweala,
  • Oluwapelumi Eniola Adurosakin,
  • Ugochukwu Innocent,
  • Conrad A. Omonhinmin,
  • Omoremime Elizabeth Dania and
  • Eziuche Amadike Ugbogu

13 June 2024

Aging is a complex biological and physiological change that leads to a loss of function in all living organisms. Although the mechanism behind the aging process is still largely unknown, scientific studies have shown that oxidative stress and age-rel...

  • Article
  • Open Access
14 Citations
134,538 Views
33 Pages

On Hens, Eggs, Temperatures and CO2: Causal Links in Earth’s Atmosphere

  • Demetris Koutsoyiannis,
  • Christian Onof,
  • Zbigniew W. Kundzewicz and
  • Antonis Christofides

13 September 2023

The scientific and wider interest in the relationship between atmospheric temperature (T) and concentration of carbon dioxide ([CO2]) has been enormous. According to the commonly assumed causality link, increased [CO2] causes a rise in T. However, re...

  • Article
  • Open Access
14 Citations
2,557 Views
43 Pages

Smart Energy Strategy for AC Microgrids to Enhance Economic Performance in Grid-Connected and Standalone Operations: A Gray Wolf Optimizer Approach

  • Sebastian Lobos-Cornejo,
  • Luis Fernando Grisales-Noreña,
  • Fabio Andrade,
  • Oscar Danilo Montoya and
  • Daniel Sanin-Villa

3 June 2025

This study proposes an optimized energy management strategy for alternating current microgrids, integrating wind generation, battery energy storage systems (BESSs), and distribution static synchronous compensators (D-STATCOMs). The objective is to mi...

  • Review
  • Open Access
13 Citations
4,710 Views
16 Pages

Microbiota Status and Endometrial Cancer: A Narrative Review About Possible Correlations in Affected Versus Healthy Patients

  • Carmen Imma Aquino,
  • Anthony Nicosia,
  • Arianna Ligori,
  • Agnese Immacolata Volpicelli and
  • Daniela Surico

7 November 2024

(1) Background: Microbiota could be related to tumorigenesis through the persistence of an inflammatory state, also at the endometrial level. Inflammation, in fact, is involved in the promotion of genetic instability and in a favorable microenvironme...

  • Review
  • Open Access
13 Citations
5,597 Views
19 Pages

Detecting Denial of Service Attacks (DoS) over the Internet of Drones (IoD) Based on Machine Learning

  • Albandari Alsumayt,
  • Naya Nagy,
  • Shatha Alsharyofi,
  • Noor Al Ibrahim,
  • Renad Al-Rabie,
  • Resal Alahmadi,
  • Roaa Ali Alesse and
  • Amal A. Alahmadi

20 September 2024

The use of Unmanned Aerial Vehicles (UAVs) or drones has increased lately. This phenomenon is due to UAVs’ wide range of applications in fields such as agriculture, delivery, security and surveillance, and construction. In this context, the sec...

  • Article
  • Open Access
13 Citations
6,429 Views
23 Pages

Application of Coffee Silverskin Cellulose/Polyacrylamide Gel Polymer Electrolytes for Rechargeable Zinc-Ion Batteries

  • Vorrada Loryuenyong,
  • Jessada Khamsawat,
  • Panuwit Danwong,
  • Achanai Buasri and
  • Prasit Pattananuwat

2 September 2024

Rechargeable zinc-ion batteries (ZIBs) have grown in popularity due to their low cost and the abundance of resources. However, there has been little research into the development of gel polymer electrolytes (GPEs) for high voltage and capacity ZIBs....

  • Article
  • Open Access
13 Citations
4,208 Views
17 Pages

T5 for Hate Speech, Augmented Data, and Ensemble

  • Tosin Adewumi,
  • Sana Sabah Sabry,
  • Nosheen Abid,
  • Foteini Liwicki and
  • Marcus Liwicki

22 September 2023

We conduct relatively extensive investigations of automatic hate speech (HS) detection using different State-of-The-Art (SoTA) baselines across 11 subtasks spanning six different datasets. Our motivation is to determine which of the recent SoTA model...

  • Systematic Review
  • Open Access
13 Citations
5,401 Views
36 Pages

3 December 2025

Artificial intelligence (AI) is transforming pharmaceutical science by shifting drug delivery research from empirical experimentation toward predictive, data-driven innovation. This review critically examines the integration of AI across formulation...

  • Review
  • Open Access
13 Citations
9,865 Views
22 Pages

Pesticides in the Environment: Benefits, Harms, and Detection Methods

  • Francis Xavier D. Verdadero,
  • Alfred Z. Agarap,
  • Czarina Nicole E. Macatingrao,
  • Isagani A. Ordonez,
  • Lady Edlenill J. Tavu,
  • David Pires and
  • Mark Angelo O. Balendres

21 November 2025

Pesticides play a critical role in food production by enhancing crop yields and protecting against pests and pathogens, such as insects, bacteria, fungi, and weeds. However, their extensive use raises significant environmental concerns. The paper rev...

  • Article
  • Open Access
13 Citations
5,567 Views
15 Pages

Deep Q-Network (DQN) Model for Disease Prediction Using Electronic Health Records (EHRs)

  • Nabil M. AbdelAziz,
  • Gehan A. Fouad,
  • Safa Al-Saeed and
  • Amira M. Fawzy

7 February 2025

Many efforts have proved that deep learning models are effective for disease prediction using electronic health records (EHRs). However, these models are not yet precise enough to predict diseases. Additionally, ethical concerns and the use of cluste...

  • Review
  • Open Access
12 Citations
10,084 Views
31 Pages

Module-Lattice-Based Key-Encapsulation Mechanism Performance Measurements

  • Naya Nagy,
  • Sarah Alnemer,
  • Lama Mohammed Alshuhail,
  • Haifa Alobiad,
  • Tala Almulla,
  • Fatima Ahmed Alrumaihi,
  • Najd Ghadra and
  • Marius Nagy

1 July 2025

Key exchange mechanisms are foundational to secure communication, yet traditional methods face challenges from quantum computing. The Module-Lattice-Based Key-Encapsulation Mechanism (ML-KEM) is a post-quantum cryptographic key exchange protocol with...

  • Article
  • Open Access
12 Citations
7,872 Views
16 Pages

The Perceptions of Generation Z University Students about Their Futures: A Qualitative Study

  • Gül Dikeç,
  • Simge Öztürk,
  • Neslihan Taşbaşı,
  • Damla Figenergül and
  • Bilal Buğrahan Güler

8 December 2023

This study explored the future-oriented perceptions of Generation Z students in a foundation university. This study was conducted using qualitative research and a phenomenological design. The study sample consisted of 11 university students over the...

  • Article
  • Open Access
12 Citations
4,542 Views
17 Pages

20 September 2023

Strain sensors play a pivotal role in quantifying stress and strain across diverse domains, encompassing engineering, industry, and medicine. Their applicability has recently extended into the realm of wearable electronics, enabling real-time monitor...

  • Review
  • Open Access
12 Citations
4,953 Views
19 Pages

Cooperating and Competing Digital Twins for Industrie 4.0 in Urban Planning Contexts

  • Otthein Herzog,
  • Matthias Jarke and
  • Siegfried Zhiqiang Wu

28 November 2023

Digital twins are emerging as a prime analysis, prediction, and control concepts for enabling the Industrie 4.0 vision of cyber-physical production systems (CPPSs). Today’s growing complexity and volatility cannot be handled by monolithic digit...

  • Article
  • Open Access
11 Citations
7,461 Views
19 Pages

Deep-Learning-Based Real-Time Visual Pollution Detection in Urban and Textile Environments

  • Md Fahim Shahoriar Titu,
  • Abdul Aziz Chowdhury,
  • S. M. Rezwanul Haque and
  • Riasat Khan

11 January 2024

The environmental physiognomy of an area can significantly diminish its aesthetic appeal, rendering it susceptible to visual pollution, the unbeaten scourge of modern urbanization. In this study, we propose using a deep learning network and a robotic...

  • Article
  • Open Access
10 Citations
2,625 Views
19 Pages

Earthquake Precursors Based on Rock Acoustic Emission and Deep Learning

  • Zihan Jiang,
  • Zhiwen Zhu,
  • Giuseppe Lacidogna,
  • Leandro F. Friedrich and
  • Ignacio Iturrioz

1 August 2025

China is one of the countries severely affected by earthquakes, making precise and timely identification of earthquake precursors essential for reducing casualties and property damage. A novel method is proposed that combines a rock acoustic emission...

  • Review
  • Open Access
10 Citations
11,346 Views
16 Pages

Recent Research on Linseed Oil Use in Wood Protection—A Review

  • Dace Cirule,
  • Ingeborga Andersone,
  • Edgars Kuka and
  • Bruno Andersons

5 September 2024

Although linseed oil (LO) has been used in wood protection for centuries, research continues to develop new and more effective formulations and treatment approaches. In the future, growing interest in LO use could be expected due to its cost and envi...

  • Review
  • Open Access
10 Citations
5,359 Views
15 Pages

15 August 2023

Among different biological methods used for advanced wastewater treatment, membrane bioreactors have demonstrated superior efficiency due to their hybrid nature, combining biological and physical processes. However, their efficient operation and cont...

  • Review
  • Open Access
9 Citations
5,220 Views
25 Pages

Governing Healthcare AI in the Real World: How Fairness, Transparency, and Human Oversight Can Coexist: A Narrative Review

  • Paolo Bailo,
  • Giulio Nittari,
  • Giuliano Pesel,
  • Emerenziana Basello,
  • Tommaso Spasari and
  • Giovanna Ricci

6 February 2026

Artificial intelligence (AI) is rapidly shifting from experimental pilots to mainstream clinical infrastructure, redefining how evidence, accountability, and ethics intersect in healthcare. This narrative review integrates insights from peer-reviewed...

  • Article
  • Open Access
9 Citations
4,759 Views
15 Pages

Enhanced Diagnosis of Thyroid Diseases Through Advanced Machine Learning Methodologies

  • Osasere Oture,
  • Muhammad Zahid Iqbal and
  • Xining (Ning) Wang

13 May 2025

Thyroid disease is a health concern related to the thyroid gland, which is vital for controlling the metabolism of the human body. Predominantly affecting women in their fourth or fifth decades of life, thyroid disease can result in physical and ment...

  • Article
  • Open Access
9 Citations
5,090 Views
15 Pages

Development of Tannic Acid Coated Polyvinylidene Fluoride Membrane for Filtration of River Water Containing High Natural Organic Matter

  • Rosmaya Dewi,
  • Norazanita Shamsuddin,
  • Muhammad Saifullah Abu Bakar,
  • Sutarat Thongratkaew,
  • Kajornsak Faungnawakij and
  • Muhammad Roil Bilad

20 November 2023

River water can be used as a source of drinking water. However, it is vital to consider the existence of natural organic matter (NOM) and its possible influence on water quality (low turbidity, high color). The level of NOM in river water significant...

  • Article
  • Open Access
9 Citations
12,396 Views
15 Pages

15 August 2024

The well-known Gaussian plume model has proven to be very useful in simulating the atmospheric dispersion of air pollutants (both gaseous and particulates). Nevertheless, the nature of the model presents problems in the actual computation of concentr...

  • Article
  • Open Access
9 Citations
3,641 Views
17 Pages

Dapagliflozin and Silymarin Ameliorate Cisplatin-Induced Nephrotoxicity via Nrf2/HO-1 Upregulation: A Preclinical Mechanistic Study

  • Shakta Mani Satyam,
  • Laxminarayana Kurady Bairy,
  • Abdul Rehman,
  • Anuradha Asokan Nair,
  • Mohamed Farook,
  • Nirmal Nachiketh Binu,
  • Sofiya Khan,
  • Mohamed Yehya and
  • Mohammed Moin Khan

8 May 2025

This study evaluated the nephroprotective potential of dapagliflozin and silymarin, alone and in combination, against cisplatin-induced kidney damage in female Wistar rats. Cisplatin was administered at 3 mg/kg weekly to all groups except the normal...

  • Systematic Review
  • Open Access
8 Citations
3,813 Views
28 Pages

7 January 2026

The integration of artificial intelligence into the Industrial Internet of Things (IIoT), supported by edge computing architectures, marks a new paradigm of intelligent automation. Tiny Machine Learning (TinyML) is emerging as a key technology that e...

  • Review
  • Open Access
8 Citations
8,816 Views
30 Pages

1 July 2025

Wilson’s disease is a rare autosomal recessive disorder of copper metabolism characterized by excessive copper accumulation in the liver, brain, and other tissues. This paper provides an overview of the primary pharmacological agents used in it...

  • Article
  • Open Access
8 Citations
5,132 Views
14 Pages

4 February 2024

Emotion classification using physiological signals is a promising approach that is likely to become the most prevalent method. Bio-signals such as those derived from Electrocardiograms (ECGs) and the Galvanic Skin Response (GSR) are more reliable tha...

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